SCHEMBL5909497

SCHEMBL5909497

CCN(CC)c1ccc(Cc2ccc(N=C=O)cc2)cc1

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 3/20 0.67
TSHR P16473 3/20 0.67
ALDH1A1 P00352 7/20 0.50
CYP1A2 P05177 1/20 0.50
ALDH3A1 P30838 1/20 0.50
ALDH1A3 P47895 1/20 0.50
CNR2 P34972 7/20 0.45
TDP1 Q9NUW8 4/20 0.40
MAPK1 P28482 2/20 0.40
GFER P55789 2/20 0.40
RECQL P46063 2/20 0.40
L3MBTL1 Q9Y468 2/20 0.40
PSMD14 O00487 1/20 0.40
CNR1 P21554 2/20 0.39
MEN1 O00255 4/20 0.38
KMT2A Q03164 4/20 0.38
KDM4E B2RXH2 4/20 0.38
MAPT P10636 3/20 0.38
LMNA P02545 3/20 0.38
GAA P10253 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2853713 0.91 ALDH1A1 (0.53) CYP3A4TSHRALDH1A1ALDH3A1ALDH1A3
Ethane SCHEMBL20537385 0.82 CYP3A4 (0.91) CYP3A4TSHRALDH1A1CYP1A2TDP1
SCHEMBL1396496 0.82 CYP3A4 (1.00) CYP3A4TSHRALDH1A1CYP1A2TDP1
SCHEMBL12852256 0.82 CYP3A4 (1.00) CYP3A4TSHRALDH1A1CYP1A2TDP1
SCHEMBL2044965 0.82 CYP3A4 (1.00) CYP3A4TSHRALDH1A1CYP1A2TDP1
SCHEMBL19943 0.82 CYP3A4 (1.00) CYP3A4TSHRALDH1A1CYP1A2TDP1
SCHEMBL18600545 0.81 CNR2 (0.47) CYP3A4TSHRALDH1A1CNR2MAPK1
SCHEMBL15489470 0.80 TDP1 (0.54) CYP3A4TSHRALDH1A1ALDH3A1ALDH1A3
Alcohol SCHEMBL28205587 0.80 CYP3A4 (0.80) CYP3A4TSHRALDH1A1CYP1A2TDP1
SCHEMBL1104244 0.80 CYP3A4 (0.67) CYP3A4TSHRALDH1A1CYP1A2TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8987362-B2 Functionalized high cis-1,4-polybutadiene prepared using novel functionalizing agents BRIDGESTONE CORP (JP) 2015-03-24 US claimed
US-20140100339-A1 FUNCTIONALIZED HIGH CIS-1,4-POLYBUTADIENE PREPARED USING NOVEL FUNCTIONALIZING AGENTS JSR CORPORATION (JP) 2014-04-10 US claimed
US-20130102736-A1 FUNCTIONALIZED HIGH CIS-1,4-POLYBUTADIENE PREPARED USING NOVEL FUNCTIONALIZING AGENTS OZAWA YOICHI (JP) 2013-04-25 US claimed
US-20060004131-A1 Functionalized high cis-1,4-polybutadiene prepared using novel functionalizing agents OZAWA YOICHI 2006-01-05 US claimed