Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | GLS | O94925 | 1/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.41 |
| ▸ | CTSK | P43235 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Cyclohexane SCHEMBL28549114 | 0.96 | TSHR (0.44) | NPC1RAB9ASMN1; SMN2LMNATSHR | |
| Cyclohexane SCHEMBL28548064 | 0.91 | LMNA (0.44) | SMN1; SMN2LMNATSHRCYP3A4ALDH1A1 | |
| Butylbenzyl SCHEMBL28279404 | 0.82 | CTSK (0.50) | SMN1; SMN2LMNATSHRCYP3A4MAPK1 | |
| SCHEMBL28061306 | 0.80 | MMP8 (0.50) | NPC1SMN1; SMN2LMNATSHRALDH1A1 | |
| SCHEMBL29024336 | 0.79 | NPC1 (0.56) | NPC1RAB9ASMN1; SMN2LMNATSHR | |
| SCHEMBL28543976 | 0.78 | LMNA (0.47) | NPC1RAB9ASMN1; SMN2LMNATSHR | |
| SCHEMBL28537168 | 0.78 | SMN1; SMN2 (0.47) | NPC1RAB9ASMN1; SMN2LMNATSHR | |
| SCHEMBL9562207 | 0.77 | NPC1 (0.51) | NPC1RAB9ASMN1; SMN2LMNATSHR | |
| SCHEMBL28277988 | 0.77 | NPC1 (0.51) | NPC1RAB9ASMN1; SMN2LMNATSHR | |
| SCHEMBL28551213 | 0.76 | LMNA (0.48) | NPC1RAB9ASMN1; SMN2LMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109553705-B | Catalyst component for olefin polymerization and preparation method thereof | 中国石油化工股份有限公司 | 2021-04-13 | — | — | CN | claimed |
| CN-109553712-B | Catalyst component for olefin polymerization and catalyst thereof | 中国石油化工股份有限公司 | 2021-03-16 | — | — | CN | claimed |