SCHEMBL28537207

SCHEMBL28537207

O=C1COC(=O)C(c2ccc(Cl)cc2)O1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.39
KMT2A Q03164 4/20 0.39
MEN1 O00255 3/20 0.39
HTT P42858 3/20 0.36
HPGD P15428 1/20 0.36
RAB9A P51151 1/20 0.34
TAAR1 Q96RJ0 1/20 0.34
SLC6A2 P23975 1/20 0.34
SLC6A4 P31645 1/20 0.34
SLC6A3 Q01959 1/20 0.34
POLB P06746 3/20 0.33
ALOX12 P18054 2/20 0.33
SMN1; SMN2 Q16637 2/20 0.33
KDM4E B2RXH2 1/20 0.33
LMNA P02545 1/20 0.33
MAPT P10636 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
SAE1 Q9UBE0 1/20 0.33
UBA2 Q9UBT2 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28545499 0.82 ALDH1A1 (0.41) ALDH1A1KMT2AMEN1HTTHPGD
SCHEMBL9303316 0.81 ALDH1A1 (0.43) ALDH1A1KMT2AMEN1HTTHPGD
SCHEMBL28911292 0.81 POLB (0.37) ALDH1A1HPGDPOLBSMN1; SMN2KDM4E
SCHEMBL28542552 0.80 MDM2 (0.40) ALDH1A1HPGDTAAR1SLC6A2SLC6A3
SCHEMBL28545946 0.78 MEN1 (0.38) ALDH1A1KMT2AMEN1POLBSMN1; SMN2
SCHEMBL28545968 0.76 MGLL (0.35) ALDH1A1
SCHEMBL28547883 0.73 SPHK1 (0.38) ALDH1A1HPGDSMN1; SMN2HSD17B10
SCHEMBL28542554 0.72 TP53 (0.41) ALDH1A1KMT2AHPGDTAAR1SLC6A2
SCHEMBL28910725 0.70 CYP19A1 (0.43) ALDH1A1KMT2AMEN1SLC6A4SLC6A3
SCHEMBL28540507 0.66 TAAR1 (0.37) ALDH1A1KMT2AMEN1HPGDTAAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109553708-B Catalyst component for olefin polymerization and preparation method thereof 中国石油化工股份有限公司 2021-04-13 CN claimed
CN-109553709-B Catalyst component for olefin polymerization and catalyst thereof 中国石油化工股份有限公司 2021-04-13 CN claimed
CN-109553707-B Catalyst component for olefin polymerization, catalyst and application 中国石油化工股份有限公司 2021-04-09 CN claimed
CN-109553708-B Catalyst component for olefin polymerization and preparation method thereof 中国石油化工股份有限公司 2021-04-13 CN disclosed
CN-109553709-B Catalyst component for olefin polymerization and catalyst thereof 中国石油化工股份有限公司 2021-04-13 CN disclosed
CN-109553707-B Catalyst component for olefin polymerization, catalyst and application 中国石油化工股份有限公司 2021-04-09 CN disclosed