SCHEMBL28545968

SCHEMBL28545968

CCCc1ccc(C2OC(=O)COC2=O)cc1

nearest known ligand 0.38

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
MGLL Q99685 1/20 0.35
CA2 P00918 1/20 0.33
PLK1 P53350 1/20 0.32
LPL P06858 2/20 0.32
LIPG Q9Y5X9 2/20 0.32
ALDH1A1 P00352 1/20 0.32
PLA2G6 O60733 2/20 0.31
PLA2G4A P47712 1/20 0.31
THRB P10828 1/20 0.31
NAAA Q02083 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28547883 0.91 SPHK1 (0.38) CA2PLK1ALDH1A1PLA2G6PLA2G4A
SCHEMBL28545946 0.88 MEN1 (0.38) MGLLALDH1A1
SCHEMBL28546594 0.83 DRD2 (0.40) PLA2G6PLA2G4A
SCHEMBL28545499 0.79 ALDH1A1 (0.41) ALDH1A1
SCHEMBL28550292 0.76 PLA2G6 (0.42) MGLLCA2ALDH1A1PLA2G6PLA2G4A
SCHEMBL28537207 0.76 ALDH1A1 (0.39) ALDH1A1
SCHEMBL28538262 0.75 S1PR3 (0.38) LPLLIPGPLA2G6PLA2G4A
SCHEMBL9303316 0.75 ALDH1A1 (0.43) CA2ALDH1A1
SCHEMBL28911292 0.75 POLB (0.37) MGLLALDH1A1
SCHEMBL28541784 0.74 MGLL (0.35) MGLLALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109553708-B Catalyst component for olefin polymerization and preparation method thereof 中国石油化工股份有限公司 2021-04-13 CN claimed
CN-109553709-B Catalyst component for olefin polymerization and catalyst thereof 中国石油化工股份有限公司 2021-04-13 CN claimed
CN-109553707-B Catalyst component for olefin polymerization, catalyst and application 中国石油化工股份有限公司 2021-04-09 CN claimed
CN-109553708-B Catalyst component for olefin polymerization and preparation method thereof 中国石油化工股份有限公司 2021-04-13 CN disclosed
CN-109553709-B Catalyst component for olefin polymerization and catalyst thereof 中国石油化工股份有限公司 2021-04-13 CN disclosed
CN-109553707-B Catalyst component for olefin polymerization, catalyst and application 中国石油化工股份有限公司 2021-04-09 CN disclosed