SCHEMBL28545499

SCHEMBL28545499

Cc1ccc(C2OC(=O)COC2=O)cc1

nearest known ligand 0.44

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.41
LMNA P02545 1/20 0.41
MAOB P27338 5/20 0.36
CYP19A1 P11511 1/20 0.36
KMT2A Q03164 4/20 0.36
MEN1 O00255 3/20 0.36
MAPT P10636 1/20 0.36
RECQL P46063 1/20 0.36
HTT P42858 1/20 0.35
HPGD P15428 2/20 0.35
RAB9A P51151 1/20 0.35
NPC1 O15118 1/20 0.34
GLA P06280 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28537207 0.82 ALDH1A1 (0.39) ALDH1A1LMNAKMT2AMEN1MAPT
SCHEMBL9303316 0.81 ALDH1A1 (0.43) ALDH1A1LMNAMAOBCYP19A1KMT2A
SCHEMBL28911292 0.81 POLB (0.37) ALDH1A1LMNAMAOBMAPTRECQL
SCHEMBL28545946 0.81 MEN1 (0.38) ALDH1A1KMT2AMEN1MAPT
SCHEMBL28910725 0.80 CYP19A1 (0.43) ALDH1A1MAOBCYP19A1KMT2AMEN1
SCHEMBL28545968 0.79 MGLL (0.35) ALDH1A1
SCHEMBL28547883 0.77 SPHK1 (0.38) ALDH1A1HPGD
SCHEMBL28551112 0.74 ALDH1A1 (0.33) ALDH1A1MAPT
SCHEMBL28540507 0.72 TAAR1 (0.37) ALDH1A1KMT2AMEN1MAPTHPGD
SCHEMBL2533981 0.70 MAOB (0.38) ALDH1A1LMNAMAOBCYP19A1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109553708-B Catalyst component for olefin polymerization and preparation method thereof 中国石油化工股份有限公司 2021-04-13 CN claimed
CN-109553709-B Catalyst component for olefin polymerization and catalyst thereof 中国石油化工股份有限公司 2021-04-13 CN claimed
CN-109553707-B Catalyst component for olefin polymerization, catalyst and application 中国石油化工股份有限公司 2021-04-09 CN claimed
CN-109553708-B Catalyst component for olefin polymerization and preparation method thereof 中国石油化工股份有限公司 2021-04-13 CN disclosed
CN-109553709-B Catalyst component for olefin polymerization and catalyst thereof 中国石油化工股份有限公司 2021-04-13 CN disclosed
CN-109553707-B Catalyst component for olefin polymerization, catalyst and application 中国石油化工股份有限公司 2021-04-09 CN disclosed