Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 6/20 | 0.34 |
| ▸ | PPARG | P37231 | 2/20 | 0.34 |
| ▸ | PPARD | Q03181 | 2/20 | 0.34 |
| ▸ | PPARA | Q07869 | 2/20 | 0.34 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.33 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.33 |
| ▸ | CACNA1I | Q9P0X4 | 1/20 | 0.33 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.32 |
| ▸ | RXRB | P28702 | 2/20 | 0.32 |
| ▸ | MAP3K12 | Q12852 | 3/20 | 0.31 |
| ▸ | F9 | P00740 | 2/20 | 0.31 |
| ▸ | F10 | P00742 | 2/20 | 0.31 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.30 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28537629 | 0.78 | HCRTR1 (0.32) | MCHR1PPARGPPARDPPARAF9 | |
| SCHEMBL28422546 | 0.76 | S1PR1 (0.35) | RXRBS1PR1 | |
| SCHEMBL28894986 | 0.73 | RET (0.32) | — | |
| SCHEMBL23044980 | 0.70 | MCHR1 (0.35) | MCHR1 | |
| SCHEMBL28535034 | 0.68 | SLC6A4 (0.31) | MCHR1 | |
| SCHEMBL28427006 | 0.66 | PDE2A (0.38) | MCHR1RXRB | |
| SCHEMBL23057529 | 0.65 | ABL1 (0.37) | MCHR1 | |
| SCHEMBL30932106 | 0.65 | ABL1 (0.37) | MCHR1 | |
| SCHEMBL23044984 | 0.65 | MCHR1 (0.33) | MCHR1 | |
| SCHEMBL28910792 | 0.64 | KCNH2 (0.42) | MCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112409333-A | Phenylpyrrolidines | 湖北生物医药产业技术研究院有限公司 | 2021-02-26 | — | — | CN | disclosed |