Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 3/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.33 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.33 |
| ▸ | ACACB | O00763 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2779247 | 0.76 | ALDH1A1 (0.41) | ALDH1A1CYP3A4CYP2C9CYP2C19TSHR | |
| SCHEMBL3376906 | 0.76 | ALDH1A1 (0.38) | ALDH1A1CYP3A4CYP2C9CYP2C19TSHR | |
| SCHEMBL1994076 | 0.74 | ALDH1A1 (0.37) | ALDH1A1CYP3A4CYP2C9CYP2C19TSHR | |
| SCHEMBL2792549 | 0.74 | ALDH1A1 (0.40) | ALDH1A1CYP3A4CYP2C9CYP2C19TSHR | |
| SCHEMBL2903934 | 0.71 | — | — | |
| SCHEMBL5606423 | 0.71 | ALDH1A1 (0.34) | ALDH1A1TSHRMAPK1MEN1KMT2A | |
| SCHEMBL27351391 | 0.69 | ALDH1A1 (0.41) | ALDH1A1CYP3A4CYP2C9CYP2C19TSHR | |
| SCHEMBL4909167 | 0.69 | ALDH1A1 (0.44) | ALDH1A1CYP3A4CYP2C9CYP2C19TSHR | |
| SCHEMBL3319888 | 0.67 | ALDH1A1 (0.40) | ALDH1A1CYP3A4CYP2C9CYP2C19TSHR | |
| SCHEMBL8766001 | 0.66 | ALDH1A1 (0.42) | ALDH1A1CYP3A4CYP2C9CYP2C19TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107899066-B | Cationic polyhydroxy polymer embolism microsphere and preparation method thereof | 苏州恒瑞迦俐生生物医药科技有限公司 | 2021-02-09 | — | — | CN | disclosed |