Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.36 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.36 |
| ▸ | ACACB | O00763 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | TGM2 | P21980 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2792549 | 0.82 | ALDH1A1 (0.40) | ALDH1A1CYP3A4CYP2C9CYP2C19TSHR | |
| SCHEMBL3376906 | 0.80 | ALDH1A1 (0.38) | ALDH1A1CYP3A4CYP2C9CYP2C19TSHR | |
| SCHEMBL1994076 | 0.78 | ALDH1A1 (0.37) | ALDH1A1CYP3A4CYP2C9CYP2C19TSHR | |
| SCHEMBL4909167 | 0.77 | ALDH1A1 (0.44) | ALDH1A1CYP3A4CYP2C9CYP2C19TSHR | |
| SCHEMBL28537745 | 0.76 | ALDH1A1 (0.35) | ALDH1A1CYP3A4CYP2C9CYP2C19TSHR | |
| SCHEMBL9141611 | 0.74 | ALDH1A1 (0.38) | ALDH1A1TSHRKMT2AMAPK1PKM | |
| SCHEMBL22702010 | 0.73 | PKM (0.44) | ALDH1A1CYP3A4CYP2C9CYP2C19TSHR | |
| SCHEMBL460924 | 0.72 | ALDH1A1 (0.53) | ALDH1A1CYP3A4CYP2C9CYP2C19TSHR | |
| SCHEMBL1907643 | 0.72 | ALDH1A1 (0.44) | ALDH1A1CYP3A4CYP2C9CYP2C19TSHR | |
| Acrylic Acid Ethyl Ester SCHEMBL21611349 | 0.72 | TSHR (0.43) | ALDH1A1CYP3A4CYP2C9CYP2C19TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9017726-B2 | Biodegradable and thermosensitive poly(organophosphazene)-superparamagnetic nanoparticle complex, preparation method and use thereof | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2015-04-28 | — | — | US | disclosed |
| US-8586020-B2 | Poly(organophosphazene) composition for biomaterials | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2013-11-19 | — | — | US | disclosed |
| US-20130004455-A1 | POLY(ORGANOPHOSPHAZENE) COMPOSITION FOR BIOMATERIALS | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2013-01-03 | — | — | US | disclosed |
| EP-2540764-A2 | Poly(organophosphazene) composition for biomaterials | Korea Institute of Science and Technology (KR) | 2013-01-02 | — | — | EP | disclosed |
| US-8313771-B2 | Phosphazene hydrogels with chemical corss-link, preparation method thereof and use thereof | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2012-11-20 | — | — | US | disclosed |
| US-20120121517-A1 | BIODEGRADABLE AND THERMOSENSITIVE POLY(ORGANOPHOSPHAZENE)-SUPERPARAMAGNETIC NANOPARTICLE COMPLEX, PREPARATION METHOD AND USE THEREOF | Korean Institute of Science and Technology of Seoul, Republic of Korea | 2012-05-17 | — | — | US | disclosed |
| US-20100297155-A1 | PHOSPHAZENE HYDROGELS WITH CHEMICAL CORSS-LINK, PREPARATION METHOD THEREOF AND USE THEREOF | DECA ITALIA S.R.L. (IT) | 2010-11-25 | — | — | US | disclosed |
| EP-2155806-A1 | PHOSPHAZENE HYDROGELS WITH CHEMICAL CORSS -LINK, PREPARATION METHOD THEREOF AND USE THEREOF | Korea Institute of Science and Technology (KR) | 2010-02-24 | — | — | EP | disclosed |
| WO-2008153278-A1 | PHOSPHAZENE HYDROGELS WITH CHEMICAL CORSS -LINK, PREPARATION METHOD THEREOF AND USE THEREOF | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2008-12-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130004455-A1 | POLY(ORGANOPHOSPHAZENE) COMPOSITION FOR BIOMATERIALS | PHOSPHO1, PGLS, PHYKPL | ALDH1A1 2323/4885CYP3A4 1110/4885CYP2C9 1320/4885 |
| US-20120121517-A1 | BIODEGRADABLE AND THERMOSENSITIVE POLY(ORGANOPHOSPHAZENE)-SUPERPARAMAGNETIC NANOPARTICLE COMPLEX, PREPARATION METHOD AND USE THEREOF | PHOSPHO1, HSPA2, FEM1B | ALDH1A1 4557/4885CYP3A4 3392/4885CYP2C9 2806/4885 |
| US-20100297155-A1 | PHOSPHAZENE HYDROGELS WITH CHEMICAL CORSS-LINK, PREPARATION METHOD THEREOF AND USE THEREOF | PRUNE1, PHYKPL, PAPSS1 | ALDH1A1 750/4885CYP3A4 619/4885CYP2C9 233/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.