Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | APP | P05067 | 2/20 | 0.39 |
| ▸ | THRB | P10828 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | AR | P10275 | 1/20 | 0.35 |
| ▸ | AOC2 | O75106 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.33 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28727720 | 0.86 | THRB (0.54) | TSHRCYP2C9THRBRAB9ASMN1; SMN2 | |
| SCHEMBL19944466 | 0.84 | CYP2C9 (0.53) | TSHRCYP2C9THRBMAPTKDM4E | |
| SCHEMBL13383393 | 0.84 | MAPT (0.46) | THRBNPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL19944362 | 0.83 | ACACB (0.46) | TDP1THRBNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL19944439 | 0.83 | ADRB2 (0.48) | TDP1THRBNPSR1LMNAALDH1A1 | |
| SCHEMBL19944710 | 0.82 | THRB (0.48) | TSHRTHRBTP53 | |
| SCHEMBL28574458 | 0.82 | TDP1 (0.43) | TSHRTDP1APPTHRBNPC1 | |
| SCHEMBL28739785 | 0.81 | CYP2C9 (0.36) | TSHRTDP1CYP2C9THRBNPC1 | |
| SCHEMBL28537147 | 0.81 | TDP1 (0.40) | TSHRTDP1CYP2C9APPNPC1 | |
| SCHEMBL12607101 | 0.80 | THRB (0.41) | TSHRCYP2C9THRBARMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109641855-B | Azo compounds, polymers, and processes for their preparation and use | 东莞东阳光医疗智能器件研发有限公司 | 2022-04-29 | — | — | CN | disclosed |
| CN-110382628-B | Polymerizable dye compound, preparation method, polymer containing dye and application | 东莞东阳光医疗智能器件研发有限公司 | 2021-03-02 | — | — | CN | disclosed |