Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 7/20 | 0.45 |
| ▸ | NPC1 | O15118 | 5/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | GBA1 | P04062 | 1/20 | 0.42 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.42 |
| ▸ | HCAR3 | P49019 | 3/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28541779 | 0.92 | HCAR3 (0.46) | RAB9ANPC1TSHRHCAR3PKM | |
| SCHEMBL28400972 | 0.81 | LMNA (0.37) | RAB9ANPC1 | |
| SCHEMBL28154048 | 0.77 | GBA1 (0.41) | RAB9ANPC1TSHRGBA1SSTR4 | |
| SCHEMBL10632091 | 0.76 | HRH3 (0.47) | RAB9ANPC1TSHRGBA1SSTR4 | |
| SCHEMBL28152938 | 0.76 | RAB9A (0.50) | RAB9ANPC1TSHRGBA1SSTR4 | |
| SCHEMBL28635345 | 0.75 | HCAR3 (0.43) | RAB9ANPC1TSHRHCAR3PKM | |
| SCHEMBL31688980 | 0.74 | TSHR (0.50) | RAB9ANPC1TSHRPKMSMN1; SMN2 | |
| SCHEMBL15458128 | 0.74 | ATM (0.46) | RAB9ANPC1TSHRGBA1SSTR4 | |
| SCHEMBL26097018 | 0.74 | TSHR (0.54) | RAB9ANPC1TSHRHCAR3PKM | |
| SCHEMBL2714323 | 0.73 | TSHR (0.65) | RAB9ANPC1TSHRHCAR3PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112384509-B | Furin inhibitors | 葛兰素史密斯克莱知识产权发展有限公司 | 2024-04-30 | — | — | CN | disclosed |
| CN-112384509-A | Furin inhibitors | 葛兰素史密斯克莱知识产权发展有限公司 | 2021-02-19 | — | — | CN | disclosed |