Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | XDH | P47989 | 2/20 | 0.47 |
| ▸ | MYC | P01106 | 2/20 | 0.45 |
| ▸ | MAX | P61244 | 2/20 | 0.45 |
| ▸ | AR | P10275 | 1/20 | 0.44 |
| ▸ | PELP1 | Q8IZL8 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.42 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28538750 | 0.90 | XDH (0.47) | MAPTALDH1A1KDM4EXDHLMNA | |
| SCHEMBL28544132 | 0.86 | ALDH1A1 (0.48) | MAPTALDH1A1XDHMYCMAX | |
| SCHEMBL28910328 | 0.86 | PDK1 (0.52) | MAPTALDH1A1KDM4EXDHLMNA | |
| SCHEMBL28911094 | 0.85 | MAPT (0.52) | MAPTALDH1A1KDM4ELMNAKMT2A | |
| SCHEMBL28539571 | 0.84 | MAPT (0.59) | MAPTALDH1A1KDM4ELMNAKMT2A | |
| SCHEMBL28547234 | 0.83 | MAPT (0.60) | MAPTALDH1A1KDM4ELMNAKMT2A | |
| SCHEMBL28552180 | 0.83 | XDH (0.46) | MAPTALDH1A1KDM4EXDHLMNA | |
| SCHEMBL28542514 | 0.82 | MAPT (0.59) | MAPTALDH1A1KDM4ELMNAKMT2A | |
| SCHEMBL28543611 | 0.82 | CTSV (0.56) | MAPTALDH1A1KDM4ELMNAKMT2A | |
| SCHEMBL28451159 | 0.81 | MYC (0.58) | ALDH1A1MYCMAXARPELP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109721586-B | 5-benzyl-3-pyridyl-1H-1, 2, 4-triazole compound and preparation method and application thereof | 中国医科大学 | 2021-03-02 | — | — | CN | disclosed |