Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 5/20 | 0.73 |
| ▸ | PRSS1 | P07477 | 4/20 | 0.73 |
| ▸ | PRSS3 | P35030 | 4/20 | 0.73 |
| ▸ | ST14 | Q9Y5Y6 | 3/20 | 0.73 |
| ▸ | PRSS2 | P07478 | 3/20 | 0.73 |
| ▸ | TMPRSS6 | Q8IU80 | 2/20 | 0.73 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.66 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.66 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.66 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.66 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.66 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.66 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.66 |
| ▸ | ITGB3 | P05106 | 8/20 | 0.51 |
| ▸ | ITGA2B | P08514 | 8/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | PLAU | P00749 | 2/20 | 0.48 |
| ▸ | MASP2 | O00187 | 1/20 | 0.48 |
| ▸ | THPO | P40225 | 1/20 | 0.48 |
| ▸ | APEX1 | P27695 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2403330 | 0.84 | F2 (1.00) | F2PRSS1PRSS3ST14PRSS2 | |
| SCHEMBL8106249 | 0.81 | F2 (0.89) | F2PRSS1PRSS3ST14PRSS2 | |
| SCHEMBL3555044 | 0.79 | F2 (0.85) | F2PRSS1PRSS3ST14PRSS2 | |
| SCHEMBL12355710 | 0.79 | F2 (1.00) | F2PRSS1PRSS3ST14PRSS2 | |
| SCHEMBL7316048 | 0.76 | F2 (0.75) | F2PRSS1PRSS3ST14PRSS2 | |
| SCHEMBL537030 | 0.75 | LMNA (0.77) | F2PRSS1PRSS3ST14PRSS2 | |
| SCHEMBL376904 | 0.75 | F2 (0.72) | F2PRSS1PRSS3ST14PRSS2 | |
| Hydrochloric Acid SCHEMBL30999366 | 0.72 | PRSS1 (0.78) | F2PRSS1PRSS3ST14PRSS2 | |
| Hydrochloric Acid SCHEMBL392375 | 0.72 | PRSS1 (0.78) | F2PRSS1PRSS3ST14PRSS2 | |
| SCHEMBL3556883 | 0.70 | F2 (0.55) | F2PRSS1PRSS3ST14PRSS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111892577-A | Compounds and methods for targeted degradation of androgen receptor | 阿尔维纳斯运营股份有限公司 | 2020-11-06 | — | — | CN | disclosed |