Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 5/20 | 0.55 |
| ▸ | PRSS1 | P07477 | 5/20 | 0.55 |
| ▸ | PRSS3 | P35030 | 5/20 | 0.55 |
| ▸ | PRSS2 | P07478 | 4/20 | 0.55 |
| ▸ | ST14 | Q9Y5Y6 | 3/20 | 0.55 |
| ▸ | TMPRSS6 | Q8IU80 | 2/20 | 0.55 |
| ▸ | AOC2 | O75106 | 1/20 | 0.53 |
| ▸ | F10 | P00742 | 2/20 | 0.50 |
| ▸ | F12 | P00748 | 1/20 | 0.50 |
| ▸ | F7 | P08709 | 1/20 | 0.50 |
| ▸ | F3 | P13726 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.50 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.50 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.50 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.50 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.50 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.50 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.50 |
| ▸ | WDR5 | P61964 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1477782 | 0.78 | AOC2 (0.63) | AOC2LMNABLMVHLELOC | |
| Guanidine SCHEMBL4169570 | 0.77 | MAPT (0.45) | F2PRSS1PRSS3PRSS2AOC2 | |
| SCHEMBL8704862 | 0.76 | AOC2 (0.65) | AOC2LMNABLMRECQLKMT2A | |
| SCHEMBL537030 | 0.75 | LMNA (0.77) | F2PRSS1PRSS3PRSS2ST14 | |
| SCHEMBL4397630 | 0.75 | AOC2 (0.50) | AOC2LMNABLMVHLELOC | |
| SCHEMBL12263881 | 0.75 | PRSS1 (0.52) | F2PRSS1PRSS3PRSS2ST14 | |
| Hydrochloric Acid SCHEMBL8707141 | 0.75 | AOC2 (0.63) | AOC2LMNABLMRECQLKMT2A | |
| SCHEMBL27374956 | 0.75 | CYP3A4 (0.60) | F2PRSS1PRSS3PRSS2ST14 | |
| Hydrochloric Acid SCHEMBL10668867 | 0.74 | WDR5 (0.48) | F2PRSS1PRSS3PRSS2ST14 | |
| Hydrochloric Acid SCHEMBL30999366 | 0.72 | PRSS1 (0.78) | F2PRSS1PRSS3PRSS2ST14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7645776-B2 | (R)-1-{2-[3-(4-Methoxy-phenyl)-[1,2,4]oxadiazol-5-yl]-piperidin-1-yl}-2-phenoxy-ethanone; carnitine-dependent palmitoyltransferases (CPTs); reduce liver beta -oxidation, consequently inhibit gluconeogenesis and therefore counteract hyperglycemia | HOFFMANN-LA ROCHE INC. (US) | 2010-01-12 | — | — | US | disclosed |
| US-20070129544-A1 | (R)-1-{2-[3-(4-Methoxy-phenyl)-[1,2,4]oxadiazol-5-yl]-piperidin-1-yl}-2-phenoxy-ethanone; carnitine-dependent palmitoyltransferases (CPTs); reduce liver beta -oxidation, consequently inhibit gluconeogenesis and therefore counteract hyperglycemia | F. HOFFMANN-LA ROCHE AG (CH) | 2007-06-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070129544-A1 | (R)-1-{2-[3-(4-Methoxy-phenyl)-[1,2,4]oxadiazol-5-yl]-piperidin-1-yl}-2-phenoxy-ethanone; carnitine-dependent palmitoyltransferases (CPTs); reduce liver beta -oxidation, consequently inhibit gluconeogenesis and therefore counteract hyperglycemia | CPT1A, CPT1B, CPT2 | F2 3122/4885PRSS1 1242/4885PRSS3 1798/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.