Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | NNMT | P40261 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.38 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.38 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.38 |
| ▸ | PLAU | P00749 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | NOS3 | P29474 | 1/20 | 0.36 |
| ▸ | NOS2 | P35228 | 1/20 | 0.36 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.36 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11929549 | 0.85 | ALDH1A1 (0.45) | KDM4EALDH1A1HSD17B10MAPTRAB9A | |
| SCHEMBL28503439 | 0.81 | KDM4E (0.43) | KDM4EALDH1A1GLANNMTLMNA | |
| SCHEMBL28558762 | 0.81 | LMNA (0.39) | GLANNMTLMNAMAPTMKNK1 | |
| SCHEMBL28630009 | 0.79 | ALDH1A1 (0.44) | KDM4EALDH1A1GLANNMTLMNA | |
| SCHEMBL18214844 | 0.78 | KDM4E (0.47) | KDM4EALDH1A1HSD17B10NNMTMAPT | |
| SCHEMBL28476110 | 0.78 | KDM4E (0.58) | KDM4EALDH1A1HSD17B10NNMTMAPT | |
| SCHEMBL19599653 | 0.76 | KDM4E (0.43) | KDM4EALDH1A1HSD17B10LMNAMAPT | |
| SCHEMBL28909873 | 0.76 | PLAU (0.39) | KDM4EALDH1A1GLALMNAPLAU | |
| SCHEMBL881472 | 0.76 | L3MBTL1 (0.58) | ALDH1A1HSD17B10MAPTRAB9AHPGD | |
| SCHEMBL19732860 | 0.75 | NOS3 (0.43) | KDM4EALDH1A1HSD17B10ADRA2AADRA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112236161-A | Modulators of G protein-coupled receptors | 卡莫特治疗学股份有限公司 | 2021-01-15 | — | — | CN | disclosed |