Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNMT | P11086 | 5/20 | 0.73 |
| ▸ | CD44 | P16070 | 2/20 | 0.73 |
| ▸ | MAOB | P27338 | 1/20 | 0.73 |
| ▸ | HTR2C | P28335 | 1/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.43 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.43 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.43 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.43 |
| ▸ | PRCP | P42785 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 1,2,3,4-Tetrahydroisoquinoline SCHEMBL2586959 | 0.91 | PNMT (0.66) | PNMTCD44MAOBHTR2CALOX15 | |
| 1,2,3,4-Tetrahydroisoquinoline SCHEMBL985673 | 0.90 | PNMT (0.63) | PNMTCD44MAOBHTR2CALOX15 | |
| 1,2,3,4-Tetrahydroisoquinoline SCHEMBL19085 | 0.85 | PNMT (1.00) | PNMTCD44MAOBHTR2CADRA2A | |
| Indoline SCHEMBL29360339 | 0.85 | — | — | |
| 1,2,3,4-Tetrahydroisoquinoline SCHEMBL29360217 | 0.85 | PNMT (1.00) | PNMTCD44MAOBHTR2CADRA2A | |
| 1,2,3,4-Tetrahydroisoquinoline SCHEMBL28236302 | 0.85 | PNMT (1.00) | PNMTCD44MAOBHTR2CADRA2A | |
| Indoline SCHEMBL5629 | 0.85 | — | — | |
| Indoline SCHEMBL27677476 | 0.84 | HTR2C (0.58) | PNMTCD44MAOBHTR2CALOX15 | |
| Indoline SCHEMBL23295083 | 0.83 | HTR2C (0.50) | PNMTCD44MAOBHTR2CALOX15 | |
| Indoline SCHEMBL11401846 | 0.83 | HTR2C (0.50) | PNMTCD44MAOBHTR2CALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112645948-B | Synthesis method of polycyclic compound containing indoline structure | 常州大学 | 2022-04-05 | — | — | CN | disclosed |
| CN-112645948-A | Synthesis method of polycyclic compound containing indoline structure | 常州大学 | 2021-04-13 | — | — | CN | disclosed |