Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | RBP1 | P09455 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Fluoride Ion SCHEMBL18693988 | 0.79 | ALDH1A1 (0.33) | HTTRBP1ALDH1A1 | |
| SCHEMBL28541299 | 0.78 | LMNA (0.30) | — | |
| Hydrochloric Acid SCHEMBL18493341 | 0.73 | HTT (0.36) | HTTRBP1ALDH1A1 | |
| SCHEMBL12188159 | 0.72 | SMN1; SMN2 (0.41) | HTTRBP1ALDH1A1 | |
| SCHEMBL10190515 | 0.72 | ALDH1A1 (0.32) | HTTALDH1A1 | |
| SCHEMBL8267937 | 0.72 | SLC18A3 (0.41) | HTTRBP1ALDH1A1 | |
| SCHEMBL22544377 | 0.71 | SIGMAR1 (0.47) | — | |
| SCHEMBL772961 | 0.71 | HTT (0.37) | HTTRBP1ALDH1A1 | |
| SCHEMBL18717641 | 0.70 | ALDH1A1 (0.36) | HTTRBP1ALDH1A1 | |
| SCHEMBL14487940 | 0.69 | KDM1A (0.40) | HTTRBP1ALDH1A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117561261-A | Pyrazolo [1,5-a ] pyrimidine derivatives as sigma ligands | 塔拉森调理公司 | 2024-02-13 | — | — | CN | disclosed |
| CN-112566906-A | Substituted quinazolinone derivatives and their use as positive allosteric modulators of MGLUR4 | 多曼治疗学公司 | 2021-03-26 | — | — | CN | disclosed |