Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8736233 | 0.75 | NCF1 (0.52) | LMNA | |
| SCHEMBL8267937 | 0.72 | SLC18A3 (0.41) | ALDH1A1HTT | |
| SCHEMBL28542124 | 0.72 | HTT (0.33) | ALDH1A1HTT | |
| SCHEMBL96704 | 0.72 | NCF1 (0.52) | ALDH1A1HTTLMNA | |
| SCHEMBL17111070 | 0.71 | CHRM2 (0.30) | — | |
| SCHEMBL13935009 | 0.71 | SLC6A1 (0.37) | ALDH1A1 | |
| SCHEMBL85227 | 0.70 | HTT (0.33) | ALDH1A1HTTLMNA | |
| SCHEMBL13654264 | 0.70 | NCF1 (0.34) | ALDH1A1HTTLMNA | |
| SCHEMBL27273747 | 0.70 | HTT (0.33) | ALDH1A1HTTLMNA | |
| SCHEMBL10107071 | 0.69 | JAK2 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120040897-A1 | NOVEL DERIVATIVES OF ACYL CYANOPYRROLIDINES | SUN PHARMA ADVANCED RESEARCH COMPANY LTD. (IN) | 2012-02-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120040897-A1 | NOVEL DERIVATIVES OF ACYL CYANOPYRROLIDINES | NR1D2, STARD10, NR1D1 | ALDH1A1 3340/4885HTT 1367/4885LMNA 2921/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.