Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | RHOC | P08134 | 1/20 | 0.41 |
| ▸ | RHOA | P61586 | 1/20 | 0.41 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | CCR1 | P32246 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2860829 | 0.91 | TNKS (0.42) | LMNAATMTDP1MAPTKMT2A | |
| SCHEMBL2848615 | 0.91 | MAPT (0.44) | ATMNPC1MAPTKMT2AMEN1 | |
| SCHEMBL2850258 | 0.90 | MAPT (0.51) | CYP1A2MAPTKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL2856756 | 0.90 | ACHE (0.40) | LMNAATMTDP1MAPTKMT2A | |
| SCHEMBL2853258 | 0.89 | NPY5R (0.45) | NPC1RAB9AMAPTKMT2AMEN1 | |
| SCHEMBL2860210 | 0.89 | NR3C1 (0.42) | RAB9AMAPTKMT2AMEN1TP53 | |
| SCHEMBL2854572 | 0.88 | RAB9A (0.44) | CYP1A2NPC1RAB9AMAPTKMT2A | |
| SCHEMBL2854221 | 0.88 | MAPT (0.51) | LMNATDP1MAPTKMT2AMEN1 | |
| SCHEMBL2852565 | 0.88 | MAPT (0.42) | LMNACYP1A2NPC1RAB9AMAPT | |
| SCHEMBL2858311 | 0.88 | RAB9A (0.47) | ATMNPC1RAB9AMAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | claimed |