Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XDH | P47989 | 2/20 | 0.45 |
| ▸ | MRGPRX4 | Q96LA9 | 3/20 | 0.44 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.38 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28911861 | 0.88 | XDH (0.48) | XDHMRGPRX4TSHR | |
| SCHEMBL28552545 | 0.86 | XDH (0.52) | XDHMRGPRX4SCN9APTGER1KDM4E | |
| Hydrochloric Acid SCHEMBL28547586 | 0.79 | HDAC8 (0.42) | PTGER1NR4A2HDAC8KDM4EPOLB | |
| SCHEMBL28554957 | 0.77 | XDH (0.52) | XDHPTGER1KDM4EPOLBHSD17B10 | |
| SCHEMBL28550907 | 0.76 | XDH (0.50) | XDHTSHR | |
| SCHEMBL28544806 | 0.76 | XDH (0.46) | XDHKDM4ETSHR | |
| SCHEMBL28552594 | 0.75 | ALDH1A1 (0.54) | XDHKDM4ETSHR | |
| SCHEMBL28539223 | 0.75 | XDH (0.45) | XDHKDM4ETSHR | |
| SCHEMBL28556756 | 0.74 | XDH (0.58) | XDHMRGPRX4SLC6A4 | |
| SCHEMBL28542901 | 0.74 | ALDH1A1 (0.65) | XDHKDM4EPOLBTSHRHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110156757-B | Tetrazole type xanthine oxidase inhibitor compound and preparation method and application thereof | 沈阳海诺威医药科技有限公司 | 2021-04-16 | — | — | CN | disclosed |