Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 2/20 | 0.71 |
| ▸ | HSD11B1 | P28845 | 12/20 | 0.62 |
| ▸ | NPC1 | O15118 | 2/20 | 0.56 |
| ▸ | RAB9A | P51151 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | CA4 | P22748 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | MMP2 | P08253 | 1/20 | 0.50 |
| ▸ | MMP7 | P09237 | 1/20 | 0.50 |
| ▸ | MMP14 | P50281 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6278347 | 0.93 | HSD11B1 (0.71) | RECQLHSD11B1NPC1RAB9AALDH1A1 | |
| SCHEMBL452973 | 0.87 | HSD11B1 (0.77) | RECQLHSD11B1NPC1RAB9AALDH1A1 | |
| SCHEMBL29609513 | 0.85 | HSD11B1 (0.74) | RECQLHSD11B1NPC1RAB9AALDH1A1 | |
| SCHEMBL28392708 | 0.84 | RECQL (0.73) | RECQLHSD11B1NPC1RAB9AALDH1A1 | |
| SCHEMBL4966036 | 0.84 | RECQL (0.73) | RECQLHSD11B1NPC1RAB9AALDH1A1 | |
| SCHEMBL6203319 | 0.83 | HSD11B1 (0.71) | RECQLHSD11B1NPC1ALDH1A1KMT2A | |
| SCHEMBL6199060 | 0.83 | KMT2A (0.73) | RECQLHSD11B1NPC1RAB9AALDH1A1 | |
| SCHEMBL27933192 | 0.83 | HSD11B1 (0.88) | RECQLHSD11B1ALDH1A1KMT2AMEN1 | |
| SCHEMBL28392126 | 0.83 | HSD11B1 (0.87) | RECQLHSD11B1NPC1RAB9AALDH1A1 | |
| SCHEMBL6201887 | 0.83 | HSD11B1 (0.87) | RECQLHSD11B1NPC1RAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111978216-B | Preparation method of beta-carbonyl sulfone compound | 西南医科大学 | 2023-02-03 | — | — | CN | disclosed |
| CN-113307749-B | Method for synthesizing beta-ketosulfone derivative under mild condition and obtained beta-ketosulfone derivative | 佛山湘潭大学绿色智造研究院 | 2022-09-09 | — | — | CN | disclosed |
| CN-113307749-A | Method for synthesizing beta-ketosulfone derivative under mild condition and obtained beta-ketosulfone derivative | 佛山湘潭大学绿色智造研究院 | 2021-08-27 | — | — | CN | disclosed |
| CN-111978216-A | Preparation method of beta-carbonyl sulfone compound | 西南医科大学 | 2020-11-24 | — | — | CN | disclosed |