Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.73 |
| ▸ | HSD11B1 | P28845 | 3/20 | 0.71 |
| ▸ | RECQL | P46063 | 2/20 | 0.71 |
| ▸ | LMNA | P02545 | 1/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.67 |
| ▸ | PKM | P14618 | 2/20 | 0.67 |
| ▸ | MAPT | P10636 | 1/20 | 0.61 |
| ▸ | NPC1 | O15118 | 1/20 | 0.57 |
| ▸ | RAB9A | P51151 | 1/20 | 0.57 |
| ▸ | CA9 | Q16790 | 3/20 | 0.53 |
| ▸ | CA1 | P00915 | 2/20 | 0.53 |
| ▸ | CA2 | P00918 | 2/20 | 0.53 |
| ▸ | CA12 | O43570 | 2/20 | 0.53 |
| ▸ | CA4 | P22748 | 1/20 | 0.53 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | APEX1 | P27695 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29012562 | 0.92 | HSD11B1 (0.83) | KMT2AHSD11B1RECQLLMNAALDH1A1 | |
| SCHEMBL28825174 | 0.84 | KMT2A (1.00) | KMT2AHSD11B1RECQLLMNAALDH1A1 | |
| SCHEMBL6203319 | 0.84 | HSD11B1 (0.71) | KMT2AHSD11B1RECQLLMNAALDH1A1 | |
| SCHEMBL29012568 | 0.84 | KMT2A (0.73) | KMT2AHSD11B1RECQLLMNAALDH1A1 | |
| SCHEMBL6223332 | 0.84 | KMT2A (0.73) | KMT2AHSD11B1RECQLLMNAALDH1A1 | |
| SCHEMBL28543793 | 0.83 | RECQL (0.71) | KMT2AHSD11B1RECQLALDH1A1NPC1 | |
| SCHEMBL2422002 | 0.83 | RECQL (1.00) | KMT2AHSD11B1RECQLLMNAALDH1A1 | |
| SCHEMBL6202982 | 0.83 | HSD11B1 (1.00) | KMT2AHSD11B1RECQLLMNAALDH1A1 | |
| SCHEMBL6278347 | 0.83 | HSD11B1 (0.71) | KMT2AHSD11B1RECQLALDH1A1NPC1 | |
| SCHEMBL29609963 | 0.82 | RECQL (0.97) | KMT2AHSD11B1RECQLLMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111978216-B | Preparation method of beta-carbonyl sulfone compound | 西南医科大学 | 2023-02-03 | — | — | CN | disclosed |
| CN-109748829-B | Preparation method of oxalyl sulfonyl hydrazide and application of oxalyl sulfonyl hydrazide in olefin sulphonation reaction | 上海麦豪新材料科技有限公司 | 2021-08-17 | — | — | CN | disclosed |
| CN-109232331-B | Process for preparing β -ketosulfone or β -hydroxysulfone by reaction of substituted olefin with sulfonyl hydrazide derivative | 江苏大学 | 2020-06-09 | — | — | CN | disclosed |
| US-20050272036-A1 | Ketones | ASTRAZENECA AB (SE) | 2005-12-08 | — | — | US | disclosed |
| EP-1549600-A1 | KETONES | AstraZeneca AB (SE) | 2005-07-06 | — | — | EP | disclosed |
| WO-2004011410-A1 | CHEMICAL COMPOUNDS | ASTRAZENECA AB (SE) | 2004-02-05 | — | — | WO | disclosed |