Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4A | O75164 | 1/20 | 0.42 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.30 |
| ▸ | FAAH | O00519 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21847057 | 0.95 | KDM4A (0.36) | KDM4AKDM4C | |
| SCHEMBL5183458 | 0.73 | PRMT3 (0.38) | — | |
| SCHEMBL19914456 | 0.72 | KDM4A (0.55) | KDM4AKDM4CALDH1A1EPHX1 | |
| SCHEMBL20000719 | 0.71 | KDM4A (0.38) | KDM4AKDM4CALDH1A1 | |
| SCHEMBL12750810 | 0.71 | KDM4A (0.42) | KDM4AKDM4CALDH1A1MEN1KMT2A | |
| SCHEMBL13292130 | 0.70 | KDM4A (0.58) | KDM4AKDM4CALDH1A1EPHX1 | |
| SCHEMBL20197677 | 0.70 | KDM4A (0.40) | KDM4AKDM4CALDH1A1 | |
| Hydrochloric Acid SCHEMBL25170217 | 0.69 | KDM4A (0.45) | KDM4AKDM4CALDH1A1MEN1KMT2A | |
| SCHEMBL27580340 | 0.69 | ALDH1A1 (0.38) | ALDH1A1POLBSMN1; SMN2MEN1KMT2A | |
| SCHEMBL13850925 | 0.69 | ALDH1A1 (0.36) | ALDH1A1POLBSMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108707139-B | Aminopyrimidine compound and preparation method and application thereof | 北京鞍石生物科技有限责任公司 | 2021-04-06 | — | — | CN | disclosed |