Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT3 | O60678 | 1/20 | 0.38 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.38 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.38 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.38 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7024069 | 0.77 | FAAH (0.39) | — | |
| SCHEMBL227134 | 0.76 | ALDH1A1 (0.35) | — | |
| SCHEMBL829692 | 0.75 | PRMT3 (0.44) | PRMT3CARM1PRMT6PRMT1PRMT8 | |
| SCHEMBL28778447 | 0.74 | FAAH (0.44) | — | |
| SCHEMBL21847057 | 0.74 | KDM4A (0.36) | — | |
| SCHEMBL21847054 | 0.74 | PRMT3 (0.32) | PRMT3CARM1PRMT6PRMT1PRMT8 | |
| SCHEMBL144324 | 0.74 | PRMT3 (0.42) | PRMT3CARM1PRMT6PRMT1PRMT8 | |
| SCHEMBL28544299 | 0.73 | KDM4A (0.42) | — | |
| Trifluoroacetic Acid SCHEMBL5284946 | 0.72 | PRMT3 (0.58) | PRMT3CARM1PRMT6PRMT1PRMT8 | |
| Trifluoroacetic Acid SCHEMBL27617461 | 0.72 | PRMT3 (0.58) | PRMT3CARM1PRMT6PRMT1PRMT8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1799699-A1 | ANALOGS OF 17-HYDROXYWORTMANNIN AS PI3K INHIBITORS | Wyeth (US) | 2007-06-27 | — | — | EP | disclosed |
| WO-2006044453-A1 | ANALOGS OF 17-HYDROXYWORTMANNIN AS PI3K INHIBITORS | WYETH (US) | 2006-04-27 | — | — | WO | disclosed |