Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | METAP2 | P50579 | 4/20 | 0.34 |
| ▸ | METAP1 | P53582 | 4/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.33 |
| ▸ | PLA2G5 | P39877 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | ALPG | P10696 | 1/20 | 0.32 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.32 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.32 |
| ▸ | BIRC2 | Q13490 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28507143 | 0.89 | ALDH1A1 (0.44) | HCAR2SMN1; SMN2TSHRNPSR1PLA2G2A | |
| SCHEMBL27491441 | 0.84 | METAP2 (0.44) | GAAMETAP2METAP1 | |
| SCHEMBL5813322 | 0.80 | GAA (0.43) | HCAR2GAATSHRMETAP2METAP1 | |
| SCHEMBL5813330 | 0.80 | GAA (0.43) | HCAR2GAATSHRMETAP2METAP1 | |
| SCHEMBL20188172 | 0.78 | CAD (0.40) | HCAR2SMN1; SMN2LMNATSHRMETAP2 | |
| SCHEMBL28470159 | 0.77 | CA14 (0.46) | SMN1; SMN2LMNATSHRALDH1A1HTT | |
| SCHEMBL19190109 | 0.75 | HCAR2 (0.38) | HCAR2SMN1; SMN2LMNATSHRNPSR1 | |
| SCHEMBL807672 | 0.75 | HCAR2 (0.38) | HCAR2GAASMN1; SMN2LMNATSHR | |
| SCHEMBL807261 | 0.75 | HCAR2 (0.38) | HCAR2SMN1; SMN2LMNATSHRNPSR1 | |
| SCHEMBL28565871 | 0.74 | ALDH1A1 (0.44) | SMN1; SMN2TSHRNPSR1ALDH1A1ALPG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109293525-B | Micro-channel reactor and method for preparing N-alkoxy oxalyl alanine ester by using same | 山东新和成精化科技有限公司 | 2021-04-20 | — | — | CN | disclosed |