Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 4/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.41 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2850383 | 0.92 | KMT2A (0.47) | KDRMAPTLMNAPKMKMT2A | |
| SCHEMBL2853248 | 0.89 | MAPT (0.48) | GAAMAPTLMNAPKMKMT2A | |
| SCHEMBL2856280 | 0.84 | MAPK14 (0.55) | KDRL3MBTL1GAAMAPTKMT2A | |
| SCHEMBL2856274 | 0.83 | MAPT (0.49) | L3MBTL1GAAMAPTLMNAPKM | |
| SCHEMBL2859086 | 0.82 | LMNA (0.48) | GAAMAPTLMNAPKMKMT2A | |
| SCHEMBL2861253 | 0.82 | MAPT (0.53) | GAAMAPTLMNAPKMPOLB | |
| SCHEMBL2850858 | 0.82 | KDR (0.48) | KDRL3MBTL1GAAMAPTLMNA | |
| SCHEMBL2852672 | 0.81 | MAPT (0.60) | GAAMAPTLMNAPKMKMT2A | |
| SCHEMBL2856509 | 0.80 | MAPT (0.48) | GAAMAPTLMNAPKMPOLB | |
| SCHEMBL2854695 | 0.79 | MAPT (0.50) | GAAMAPTLMNAPKMPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | claimed |