Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTK2 | Q05397 | 1/20 | 0.51 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.48 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.48 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.48 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.48 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.43 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.43 |
| ▸ | FSCN1 | Q16658 | 1/20 | 0.43 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.41 |
| ▸ | ABL1 | P00519 | 2/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9753194 | 0.81 | SORT1 (0.53) | PTK2SORT1KDM4ELMNAL3MBTL1 | |
| SCHEMBL27342111 | 0.81 | SCN10A (0.51) | SCN10ASORT1KDM4EMAPTL3MBTL1 | |
| SCHEMBL21723677 | 0.81 | ALDH1A1 (0.51) | SORT1KDM4ELMNAMAPTNPC1 | |
| SCHEMBL28552164 | 0.80 | RAB9A (0.45) | SORT1LMNAMAPTL3MBTL1NPC1 | |
| SCHEMBL1269767 | 0.78 | RAB9A (0.60) | KDM4ELMNAMAPTL3MBTL1NPC1 | |
| SCHEMBL27398574 | 0.78 | PTK2 (0.51) | PTK2SCN9ASCN2ASCN3ASCN10A | |
| SCHEMBL2019170 | 0.78 | KDM4E (0.46) | PTK2SCN9ASCN2ASCN3ASCN10A | |
| SCHEMBL7092192 | 0.78 | SMN1; SMN2 (0.48) | PTK2SORT1KDM4ELMNAMAPT | |
| SCHEMBL19736135 | 0.78 | GRM5 (0.50) | PTK2SCN9ASCN2ASCN3ASCN10A | |
| SCHEMBL9974219 | 0.78 | KDM4E (0.46) | PTK2SCN9ASCN2ASCN3ASCN10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112654354-A | 1,3,4, 9-tetrahydro-2H-pyrido [3,4-b ] indole derivative compound and application thereof | 菲尼克思药业股份有限公司 | 2021-04-13 | — | — | CN | disclosed |