Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.47 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | TOP2A | P11388 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | SPR | P35270 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | IDO1 | P14902 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2852556 | 0.93 | TDP1 (0.44) | ALDH1A1MEN1KMT2ANPSR1GAA | |
| SCHEMBL2859429 | 0.93 | NPC1 (0.46) | ALDH1A1MEN1KMT2ASMN1; SMN2NPSR1 | |
| SCHEMBL2863131 | 0.92 | CNR1 (0.50) | MEN1KMT2ANPSR1HTTTAAR1 | |
| SCHEMBL2852633 | 0.90 | TAAR1 (0.57) | ALDH1A1MEN1KMT2AGAANPC1 | |
| SCHEMBL2854509 | 0.88 | KDM4E (0.50) | ALDH1A1SMN1; SMN2GAANPC1RAB9A | |
| SCHEMBL2850868 | 0.88 | ALDH1A1 (0.51) | ALDH1A1KMT2ASMN1; SMN2HTTMAPT | |
| SCHEMBL2857230 | 0.88 | KDM4E (0.44) | ALDH1A1SMN1; SMN2NPSR1HTTGAA | |
| SCHEMBL2863198 | 0.88 | CCR1 (0.50) | ALDH1A1SMN1; SMN2NPSR1KDM4EMAPT | |
| SCHEMBL2853061 | 0.88 | KDM4E (0.44) | ALDH1A1SMN1; SMN2NPC1RAB9ATAAR1 | |
| SCHEMBL2852221 | 0.87 | ALDH1A1 (0.46) | ALDH1A1MEN1KMT2ASMN1; SMN2NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | claimed |