Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 3/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2854586 | 0.93 | ALDH1A1 (0.47) | NPC1GAARAB9ATAAR1ALDH1A1 | |
| SCHEMBL2850314 | 0.92 | P2RX7 (0.42) | NPC1GAARAB9ATAAR1ALDH1A1 | |
| SCHEMBL2848475 | 0.91 | CNR1 (0.48) | NPC1GAARAB9ATAAR1NPSR1 | |
| SCHEMBL2852633 | 0.90 | TAAR1 (0.57) | NPC1GAARAB9ATAAR1ALDH1A1 | |
| SCHEMBL2854509 | 0.88 | KDM4E (0.50) | NPC1GAARAB9ATAAR1ALDH1A1 | |
| SCHEMBL2850868 | 0.88 | ALDH1A1 (0.51) | ALDH1A1HPGDSMN1; SMN2MAPTKMT2A | |
| SCHEMBL2852556 | 0.85 | TDP1 (0.44) | NPC1GAARAB9ATAAR1ALDH1A1 | |
| SCHEMBL2859726 | 0.85 | ALDH1A1 (0.46) | NPC1GAARAB9ATAAR1ALDH1A1 | |
| SCHEMBL2859644 | 0.85 | ALDH1A1 (0.43) | NPC1GAARAB9AALDH1A1KDM4E | |
| SCHEMBL2863131 | 0.85 | CNR1 (0.50) | TAAR1KDM4ENPSR1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | claimed |