Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | CASP3 | P42574 | 1/20 | 0.46 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.46 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | GABRA2 | P47869 | 5/20 | 0.42 |
| ▸ | GABRB2 | P47870 | 5/20 | 0.42 |
| ▸ | GABRP | O00591 | 4/20 | 0.42 |
| ▸ | GABRD | O14764 | 4/20 | 0.42 |
| ▸ | GABRA1 | P14867 | 4/20 | 0.42 |
| ▸ | GABRB1 | P18505 | 4/20 | 0.42 |
| ▸ | GABRG2 | P18507 | 4/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28532069 | 0.91 | ALDH1A1 (0.54) | MAPTMEN1KMT2ACASP3TRPV1 | |
| SCHEMBL28532052 | 0.89 | HTT (0.56) | MAPTMEN1KMT2ACASP3TRPV1 | |
| SCHEMBL28545378 | 0.86 | SMN1; SMN2 (0.48) | MAPTMEN1KMT2ACASP3TRPV1 | |
| SCHEMBL29031128 | 0.83 | SMN1; SMN2 (0.47) | MAPTMEN1KMT2ACASP3SENP7 | |
| SCHEMBL28543158 | 0.82 | SMN1; SMN2 (0.53) | MAPTMEN1KMT2ACASP3SENP7 | |
| SCHEMBL347328 | 0.81 | CYP1A2 (0.51) | MAPTMEN1KMT2ACASP3TRPV1 | |
| SCHEMBL29031101 | 0.81 | SMN1; SMN2 (0.52) | MAPTMEN1KMT2ALMNAKDM4E | |
| SCHEMBL28543171 | 0.80 | PDE4B (0.51) | MAPTMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL28537077 | 0.80 | SMN1; SMN2 (0.50) | MAPTMEN1KMT2ACASP3SENP7 | |
| SCHEMBL28540429 | 0.79 | MTNR1B (0.62) | MAPTMEN1KMT2ALMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111925357-B | Acylhydrazone compound, pharmaceutical composition and application thereof | 中国科学院昆明植物研究所 | 2023-06-06 | — | — | CN | disclosed |
| CN-111925357-A | Acylhydrazone compound, pharmaceutical composition and application thereof | 中国科学院昆明植物研究所 | 2020-11-13 | — | — | CN | disclosed |