SCHEMBL2854657

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL15225754	0.84	MAPK1 (0.50)	ALDH1A1SMN1; SMN2MEN1KMT2ALMNA
	SCHEMBL2858385	0.83	MAPT (0.55)	ALDH1A1SMN1; SMN2MEN1KMT2ASIGMAR1
	SCHEMBL2856092	0.83	SMN1; SMN2 (0.47)	ALDH1A1SMN1; SMN2MEN1KMT2ASIGMAR1
	SCHEMBL2866392	0.82	FKBP1A (0.50)	ALDH1A1SMN1; SMN2MEN1KMT2ALMNA
	SCHEMBL2864940	0.80	MAPT (0.48)	ALDH1A1KMT2ALMNATSHR
	SCHEMBL2866451	0.79	DRD3 (0.45)	ALDH1A1SMN1; SMN2MEN1KMT2ASIGMAR1
	SCHEMBL2862037	0.79	SMN1; SMN2 (0.41)	ALDH1A1SMN1; SMN2MEN1KMT2ALMNA
	SCHEMBL2859704	0.79	SLC6A7 (0.53)	ALDH1A1MEN1KMT2ACYP2D6
	SCHEMBL2863214	0.79	ALDH1A1 (0.41)	ALDH1A1SMN1; SMN2MEN1KMT2ASIGMAR1
	SCHEMBL2868820	0.79	SMN1; SMN2 (0.47)	ALDH1A1SMN1; SMN2MEN1KMT2ATSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.