SCHEMBL28547322

SCHEMBL28547322

[O]CC(=S)NCc1ccccc1

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.63
ALOX12 P18054 4/20 0.63
HPGD P15428 2/20 0.63
GAA P10253 4/20 0.61
MAPT P10636 3/20 0.61
MEN1 O00255 1/20 0.61
POLB P06746 1/20 0.61
KMT2A Q03164 1/20 0.61
CA12 O43570 2/20 0.59
CA1 P00915 2/20 0.59
CA2 P00918 2/20 0.59
CA9 Q16790 2/20 0.59
LMNA P02545 1/20 0.55
PKM P14618 1/20 0.55
MAOA P21397 1/20 0.53
MAOB P27338 1/20 0.53
IDO1 P14902 1/20 0.53
PLA2G1B P04054 1/20 0.52
ATG4B Q9Y4P1 1/20 0.52
MITF O75030 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3074969 0.85 ALOX12 (0.71) ALDH1A1ALOX12HPGDGAAMAPT
SCHEMBL5354786 0.81 ALOX12 (0.65) ALDH1A1ALOX12HPGDGAAMAPT
SCHEMBL3074967 0.80 GAA (0.61) ALDH1A1ALOX12HPGDGAAMAPT
SCHEMBL3057983 0.79 ALOX12 (0.63) ALDH1A1ALOX12HPGDGAAMAPT
SCHEMBL21376367 0.79 ALOX12 (0.63) ALDH1A1ALOX12HPGDGAAMAPT
SCHEMBL3070918 0.79 ALDH1A1 (0.57) ALDH1A1ALOX12HPGDGAAMAPT
SCHEMBL3057982 0.79 ALDH1A1 (0.57) ALDH1A1ALOX12HPGDGAAMAPT
SCHEMBL3064641 0.78 ALOX12 (0.74) ALDH1A1ALOX12HPGDGAAMAPT
SCHEMBL1275902 0.78 ALOX12 (1.00) ALDH1A1ALOX12HPGDGAAMAPT
SCHEMBL8847588 0.78 ALOX12 (0.74) ALDH1A1ALOX12HPGDGAAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112592305-B Organic compound and preparation method and application thereof 中南大学 2022-10-18 CN disclosed
CN-112592305-A Organic compound and preparation method and application thereof 中南大学 2021-04-02 CN disclosed