Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX12 | P18054 | 4/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.65 |
| ▸ | HPGD | P15428 | 2/20 | 0.65 |
| ▸ | GAA | P10253 | 3/20 | 0.63 |
| ▸ | MAPT | P10636 | 3/20 | 0.63 |
| ▸ | MEN1 | O00255 | 1/20 | 0.63 |
| ▸ | POLB | P06746 | 1/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.63 |
| ▸ | CA12 | O43570 | 2/20 | 0.61 |
| ▸ | CA1 | P00915 | 2/20 | 0.61 |
| ▸ | CA2 | P00918 | 2/20 | 0.61 |
| ▸ | CA9 | Q16790 | 2/20 | 0.61 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | PKM | P14618 | 1/20 | 0.57 |
| ▸ | MAOA | P21397 | 1/20 | 0.55 |
| ▸ | MAOB | P27338 | 1/20 | 0.55 |
| ▸ | IDO1 | P14902 | 1/20 | 0.55 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.53 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.53 |
| ▸ | ALPL | P05186 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3074969 | 0.86 | ALOX12 (0.71) | ALOX12ALDH1A1HPGDGAAMAPT | |
| SCHEMBL18891536 | 0.83 | POLB (0.56) | ALOX12ALDH1A1HPGDGAAMAPT | |
| SCHEMBL6064007 | 0.81 | GAA (0.55) | ALOX12ALDH1A1HPGDGAAMAPT | |
| SCHEMBL21376367 | 0.81 | ALOX12 (0.63) | ALOX12ALDH1A1HPGDGAAMAPT | |
| SCHEMBL28547322 | 0.81 | ALDH1A1 (0.63) | ALOX12ALDH1A1HPGDGAAMAPT | |
| SCHEMBL3057983 | 0.81 | ALOX12 (0.63) | ALOX12ALDH1A1HPGDGAAMAPT | |
| SCHEMBL15398598 | 0.80 | ALOX12 (0.57) | ALOX12ALDH1A1HPGDGAAMAPT | |
| SCHEMBL3064641 | 0.79 | ALOX12 (0.74) | ALOX12ALDH1A1HPGDGAAMAPT | |
| SCHEMBL1275902 | 0.79 | ALOX12 (1.00) | ALOX12ALDH1A1HPGDGAAMAPT | |
| SCHEMBL8847588 | 0.79 | ALOX12 (0.74) | ALOX12ALDH1A1HPGDGAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007120012-A1 | NOVEL COMPOUNDS, ISOMER THEREOF, OR PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF AS VANILLOID RECEPTOR ANTAGONIST; AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME | AMOREPACIFIC CORPORATION (KR) | 2007-10-25 | — | — | WO | disclosed |