SCHEMBL21376367

SCHEMBL21376367

CCC(=S)NCc1ccccc1

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX12 P18054 4/20 0.63
HPGD P15428 2/20 0.63
ALDH1A1 P00352 2/20 0.63
GAA P10253 3/20 0.61
MAPT P10636 2/20 0.61
KMT2A Q03164 2/20 0.61
POLB P06746 2/20 0.61
MEN1 O00255 1/20 0.61
SMN1; SMN2 Q16637 2/20 0.59
ALPL P05186 1/20 0.59
CA12 O43570 2/20 0.59
CA1 P00915 2/20 0.59
CA2 P00918 2/20 0.59
CA9 Q16790 2/20 0.59
IDO1 P14902 1/20 0.58
LMNA P02545 1/20 0.55
PKM P14618 1/20 0.55
L3MBTL1 Q9Y468 1/20 0.54
MAOA P21397 1/20 0.53
MAOB P27338 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3074969 0.85 ALOX12 (0.71) ALOX12HPGDALDH1A1GAAMAPT
SCHEMBL16188288 0.84 ALOX12 (0.59) ALOX12HPGDALDH1A1GAAMAPT
SCHEMBL7342753 0.82 SMN1; SMN2 (0.50) ALOX12HPGDALDH1A1GAAMAPT
SCHEMBL5354786 0.81 ALOX12 (0.65) ALOX12HPGDALDH1A1GAAMAPT
SCHEMBL6621549 0.80 PLA2G1B (0.66) HPGDKMT2APOLBMEN1LMNA
SCHEMBL28879898 0.80 RAB9A (0.66) ALOX12HPGDALDH1A1GAAMAPT
SCHEMBL3057983 0.79 ALOX12 (0.63) ALOX12HPGDALDH1A1GAAMAPT
SCHEMBL28547322 0.79 ALDH1A1 (0.63) ALOX12HPGDALDH1A1GAAMAPT
SCHEMBL3070918 0.79 ALDH1A1 (0.57) ALOX12HPGDALDH1A1GAAMAPT
SCHEMBL11204749 0.79 ALOX12 (0.57) ALOX12HPGDALDH1A1GAAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114956933-A Marker containing isotope oxygen atom and preparation method and application thereof 清华大学 2022-08-30 CN disclosed
CN-108383747-B Heavy oxygen labeled amide compound synthesized by thioamide, preparation method and application 华北水利水电大学 2021-03-09 CN disclosed
WO-2019178248-A1 INHIBITORS OF INTEGRIN ALPHA 2 BETA 1 AND METHODS OF USE THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2019-09-19 WO disclosed