SCHEMBL28547366

SCHEMBL28547366

Brc1ccccc1C1=CCC1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.46
MAPK1 P28482 3/20 0.46
PBRM1 Q86U86 1/20 0.35
IDO1 P14902 1/20 0.35
LMNA P02545 1/20 0.35
MAPT P10636 3/20 0.34
HPGD P15428 2/20 0.34
DCUN1D1 Q96GG9 2/20 0.34
KDM4E B2RXH2 1/20 0.34
GAA P10253 1/20 0.34
MPI P34949 1/20 0.34
APOBEC3G Q9HC16 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
HSD17B10 Q99714 1/20 0.34
MAOA P21397 1/20 0.34
MAOB P27338 1/20 0.34
GALR1 P47211 1/20 0.34
PARP10 Q53GL7 1/20 0.33
PARP11 Q9NR21 1/20 0.33
KDM1A O60341 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5863208 0.85 PTGS2 (0.41) ALDH1A1MAPK1PBRM1IDO1LMNA
SCHEMBL4425866 0.83 PTGS2 (0.47) ALDH1A1MAPK1TDP1GALR1
SCHEMBL14099218 0.77 ALDH1A1 (0.39) ALDH1A1MAPK1PBRM1IDO1LMNA
SCHEMBL4764267 0.76 MAPK14 (0.48) ALDH1A1MAPK1MAOAMAOB
SCHEMBL5584849 0.76 ALDH1A1 (0.38) ALDH1A1MAPK1PBRM1IDO1LMNA
SCHEMBL4790160 0.76 HTR2C (0.61) ALDH1A1MAPTKDM4EGAAHSD17B10
SCHEMBL28731693 0.73 S100A4 (0.41) ALDH1A1MAPK1TDP1PARP10PARP11
SCHEMBL358976 0.73 ALDH1A1 (0.67) ALDH1A1MAPK1PBRM1IDO1LMNA
SCHEMBL31295703 0.73 ALDH1A1 (0.67) ALDH1A1MAPK1PBRM1IDO1LMNA
SCHEMBL14973842 0.72 ALDH1A1 (0.52) ALDH1A1MAPK1PBRM1IDO1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118271184-A Dendritic structural compound, compound thereof and organic electroluminescent device 中国科学院长春应用化学研究所 2024-07-02 CN disclosed
CN-115417773-B Dendritic structural compound, compound thereof and organic electroluminescent device 中国科学院长春应用化学研究所 2024-05-28 CN disclosed
CN-115417773-A Dendritic structure compound and compound thereof, and organic electroluminescent device 中国科学院长春应用化学研究所 2022-12-02 CN disclosed
CN-108178720-B Synthetic method of 4-cyclobutyl biphenyl fluorine-containing compound 山东盛华新材料科技股份有限公司 2021-04-13 CN disclosed