Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | F2RL1 | P55085 | 1/20 | 0.40 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.38 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | GALR1 | P47211 | 1/20 | 0.35 |
| ▸ | PPARA | Q07869 | 1/20 | 0.33 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.32 |
| ▸ | IDO1 | P14902 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | MPI | P34949 | 1/20 | 0.32 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.32 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4425866 | 0.94 | PTGS2 (0.47) | PTGS2ALDH1A1MAPK1F2RL1GRM2 | |
| SCHEMBL28547366 | 0.85 | ALDH1A1 (0.46) | ALDH1A1MAPK1TDP1GALR1PBRM1 | |
| SCHEMBL28758944 | 0.84 | PTGS2 (0.51) | PTGS2F2RL1GRM2PSMB5TDP1 | |
| SCHEMBL11815728 | 0.78 | PTGS2 (0.59) | PTGS2F2RL1GRM2PSMB5TDP1 | |
| SCHEMBL11824855 | 0.75 | PTGS2 (0.45) | PTGS2F2RL1GRM2PSMB5TDP1 | |
| SCHEMBL9806271 | 0.75 | PTGS2 (0.57) | PTGS2ALDH1A1MAPK1F2RL1GRM2 | |
| SCHEMBL6757109 | 0.75 | F2RL1 (0.43) | PTGS2ALDH1A1F2RL1GRM2TDP1 | |
| SCHEMBL8784661 | 0.75 | ALDH1A1 (0.48) | PTGS2ALDH1A1F2RL1GRM2TDP1 | |
| SCHEMBL7442115 | 0.75 | F2RL1 (0.43) | PTGS2F2RL1GRM2PSMB5TDP1 | |
| SCHEMBL2329786 | 0.75 | PTGS2 (0.45) | PTGS2F2RL1GRM2PSMB5TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101235052-A | Asymmetric chirality diphosphine ligand | EVONIK DEGUSSA AG (DE) | 2008-08-06 | — | — | CN | disclosed |
| US-7081533-B2 | Phosphorus compounds used as catalysts for asymmetric hydrogenation, hydroformylation, rearrangement, alkylation, cyclization, hydrosilation, hydrocyanation or aldol condensation | DEGUSSA AG (DE) | 2006-07-25 | — | — | US | disclosed |
| EP-1311517-B1 | CYCLOALIPHATIC/AROMATIC DIPHOSPHINES AND USE THEREOF IN CATALYSIS | DEGUSSA (DE) | 2004-07-14 | — | — | EP | disclosed |
| US-20040019205-A1 | Phosphorus compounds used as catalysts for asymmetric hydrogenation, hydroformylation, rearrangement, alkylation, cyclization, hydrosilation, hydrocyanation or aldol condensation | DEGUSSA AG (DE) | 2004-01-29 | — | — | US | disclosed |
| EP-1311517-A1 | CYCLOALIPHATIC/AROMATIC DIPHOSPHINES AND USE THEREOF IN CATALYSIS | Degussa AG (DE) | 2003-05-21 | — | — | EP | disclosed |
| WO-2002014330-A1 | CYCLOALIPHATIC/AROMATIC DIPHOSPHINES AND USE THEREOF IN CATALYSIS | DEGUSSA AG (DE) | 2002-02-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040019205-A1 | Phosphorus compounds used as catalysts for asymmetric hydrogenation, hydroformylation, rearrangement, alkylation, cyclization, hydrosilation, hydrocyanation or aldol condensation | GNPAT, PNKP, PHOSPHO1 | PTGS2 3879/4885ALDH1A1 2414/4885MAPK1 4351/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.