Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FTO | Q9C0B1 | 9/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | SMAD3 | P84022 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.46 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.44 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | TYR | P14679 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15778575 | 0.90 | FTO (0.47) | FTOHPGDHTTMEN1MAPT | |
| SCHEMBL8029312 | 0.90 | FTO (0.47) | FTOHPGDHTTMEN1MAPT | |
| SCHEMBL4885766 | 0.90 | FTO (0.47) | FTOHPGDHTTMEN1MAPT | |
| 1,3-Propanediol SCHEMBL28555047 | 0.87 | FTO (0.47) | FTOHPGDHTTMEN1MAPT | |
| SCHEMBL905219 | 0.84 | FTO (0.47) | FTOHPGDHTTMEN1MAPT | |
| SCHEMBL183875 | 0.83 | FTO (0.52) | FTOHPGDHTTMEN1MAPT | |
| SCHEMBL7646663 | 0.83 | FTO (0.52) | FTOHPGDHTTMEN1MAPT | |
| SCHEMBL11310755 | 0.83 | FTO (0.52) | FTOHPGDHTTMEN1MAPT | |
| SCHEMBL1978381 | 0.83 | FTO (0.52) | FTOHPGDHTTMEN1MAPT | |
| SCHEMBL1254421 | 0.82 | FTO (0.64) | FTOHPGDHTTMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116676305-A | High specificity genome editing using chemically modified guide RNAs | 安捷伦科技有限公司 | 2023-09-01 | — | — | CN | disclosed |
| CN-116096885-A | Compositions and methods for targeting C9orf72 | 斯克里贝治疗公司 | 2023-05-09 | — | — | CN | disclosed |
| CN-109563514-B | Highly specific genome editing using chemically modified guide RNAs | 安捷伦科技有限公司 | 2023-03-10 | — | — | CN | disclosed |
| CN-115427570-A | Compositions and methods for targeting PCSK9 | 斯克里贝治疗公司 | 2022-12-02 | — | — | CN | disclosed |
| CN-115175921-A | Particle delivery system | 斯克里贝治疗公司 | 2022-10-11 | — | — | CN | disclosed |
| CN-114375334-A | Engineered CasX system | 斯克里贝治疗公司 | 2022-04-19 | — | — | CN | disclosed |
| CN-107250148-B | Guide RNAs with chemical modifications | 安捷伦科技有限公司 | 2021-04-16 | — | — | CN | disclosed |