SCHEMBL2854857

SCHEMBL2854857

CCCCCCc1cc(Cl)sc1Cl

nearest known ligand 0.42

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 4/20 0.42
TYR P14679 2/20 0.42
CYP3A4 P08684 2/20 0.42
MEN1 O00255 1/20 0.42
TP53 P04637 1/20 0.42
MAPT P10636 1/20 0.42
ALOX15 P16050 1/20 0.42
TSHR P16473 1/20 0.42
HTT P42858 1/20 0.42
KMT2A Q03164 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
LIPG Q9Y5X9 1/20 0.39
GPR35 Q9HC97 1/20 0.39
PTGS2 P35354 6/20 0.38
KAT2B Q92831 1/20 0.36
HTR2A P28223 1/20 0.36
GPR3 P46089 1/20 0.36
CYSLTR2 Q9NS75 2/20 0.36
CYSLTR1 Q9Y271 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19304364 1.00 ALOX5 (0.42) ALOX5TYRCYP3A4MEN1TP53
SCHEMBL198015 1.00 ALOX5 (0.42) ALOX5TYRCYP3A4MEN1TP53
SCHEMBL31410813 1.00 ALOX5 (0.42) ALOX5TYRCYP3A4MEN1TP53
SCHEMBL30603823 0.86 ALOX5 (0.41) ALOX5TYRCYP3A4MEN1TP53
SCHEMBL2847218 0.83 TYR (0.42) ALOX5TYRCYP3A4MEN1TP53
SCHEMBL2845020 0.83 ALOX5 (0.42) ALOX5TYRCYP3A4MEN1TP53
SCHEMBL2855414 0.83 ALOX5 (0.39) ALOX5TYRCYP3A4MEN1TP53
SCHEMBL3423745 0.83 TYR (0.42) ALOX5TYRCYP3A4MEN1TP53
SCHEMBL2847214 0.83 ALOX5 (0.39) ALOX5TYRCYP3A4MEN1TP53
SCHEMBL2848954 0.83 ALOX5 (0.42) ALOX5TYRCYP3A4MEN1TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240327323-A1 Methods of Treating of Halogen- Containing Waste Plastic to Produce Halogenated Products U. S. DEPARTMENT OF ENERGY 2024-10-03 US disclosed
CN-110003271-B Process for producing aromatic compound 住友化学株式会社 2022-05-03 CN disclosed
US-11045796-B2 Process for producing aromatic compound, and palladium complex SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2021-06-29 US disclosed
CN-108368142-B Method for producing aromatic compound and palladium complex 住友化学株式会社 2021-02-19 CN disclosed
US-20180369799-A1 PROCESS FOR PRODUCING AROMATIC COMPOUND, AND PALLADIUM COMPLEX SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2018-12-27 US disclosed
EP-3385270-A1 METHOD FOR PRODUCING AROMATIC COMPOUND, AND PALLADIUM COMPLEX Sumitomo Chemical Company, Ltd (JP) 2018-10-10 EP disclosed
EP-2871199-B1 METHOD FOR PRODUCING AROMATIC COMPOUND SUMITOMO CHEMICAL CO (JP) 2018-02-21 EP disclosed
EP-2871198-B1 METHOD FOR PRODUCING AROMATIC COMPOUND SUMITOMO CHEMICAL CO (JP) 2017-06-14 EP disclosed
US-9453103-B2 Method for producing aromatic compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2016-09-27 US disclosed
CN-104540871-B The preparation method of aromatic compound 住友化学株式会社 2016-08-24 CN disclosed
US-20100206613-A1 PROCESS FOR PREPARATION OF CONDUCTING POLYMERS BASF SE (DE) 2010-08-19 US disclosed
EP-2203499-A1 PROCESS FOR PREPARATION OF CONDUCTING POLYMERS BASF SE (DE) 2010-07-07 EP disclosed
US-20090211632-A1 PHOTOVOLTAIC DEVICE BASED ON CONFORMAL COATING OF COLUMNAR STRUCTURES THE GOVERNORS OF THE UNIVERSITY OF ALBERTA (CA) 2009-08-27 US disclosed
WO-2009100519-A1 PHOTOVOLTAIC DEVICE BASED ON CONFORMAL COATING OF COLUMNAR STRUCTURES THE GOVERNORS OF THE UNIVERSITY OF ALBERTA (CA) 2009-08-20 WO disclosed
WO-2009058115-A1 PROCESS FOR PREPARATION OF CONDUCTING POLYMERS RIEKE METALS INC. (US) 2009-05-07 WO disclosed
WO-2009056497-A1 REVERSE ADDITION PROCESS FOR PREPARATION OF REGIOREGULAR CONDUCTING POLYMERS BASF SE (DE) 2009-05-07 WO disclosed
WO-2009056496-A1 PROCESS FOR PREPARATION OF REGIOREGULAR CONDUCTING BLOCK COPOLYMERS BASF SE (DE) 2009-05-07 WO disclosed
WO-2009053468-A1 PROCESS FOR PREPARATION OF CONDUCTING POLYMERS BASF SE (DE) 2009-04-30 WO disclosed
US-20090048413-A1 Method for Production of Conjugated Polymer SUMITOMO CHEMICAL COMPANY, LIMITED 2009-02-19 US disclosed
EP-1997844-A1 METHOD FOR PRODUCTION OF CONJUGATED POLYMER Sumitomo Chemical Company, Limited (JP) 2008-12-03 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11045796-B2 Process for producing aromatic compound, and palladium complex DDT, DRD1, DRD2 ALOX5 3553/4885TYR 14/4885CYP3A4 148/4885
US-20240327323-A1 Methods of Treating of Halogen- Containing Waste Plastic to Produce Halogenated Products VCL, SLC6A12, TPO ALOX5 2783/4885TYR 150/4885CYP3A4 789/4885
US-20180369799-A1 PROCESS FOR PRODUCING AROMATIC COMPOUND, AND PALLADIUM COMPLEX DDT, DRD1, DRD2 ALOX5 3553/4885TYR 14/4885CYP3A4 148/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.