Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | AR | P10275 | 1/20 | 0.36 |
| ▸ | PELP1 | Q8IZL8 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21156963 | 0.88 | LMNA (0.40) | MAPTPOLBALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL28558130 | 0.83 | MAPT (0.41) | MAPTHPGDALDH1A1OPRK1NPSR1 | |
| SCHEMBL22121279 | 0.80 | PRSS1 (0.44) | MAPTPOLBMAPK1VCAM1KDM4E | |
| SCHEMBL3576978 | 0.79 | MAPT (0.46) | MAPTPOLBMAPK1ALDH1A1VCAM1 | |
| SCHEMBL22313285 | 0.78 | ALDH1A1 (0.56) | MAPTALDH1A1KDM4ESMN1; SMN2HTT | |
| SCHEMBL30181644 | 0.78 | ALDH1A1 (0.56) | MAPTALDH1A1KDM4ESMN1; SMN2HTT | |
| SCHEMBL21158078 | 0.77 | LMNA (0.41) | MAPTPOLBALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL30803028 | 0.77 | LMNA (0.41) | MAPTPOLBALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL1458078 | 0.76 | VCAM1 (0.49) | MAPTPOLBMAPK1HPGDALDH1A1 | |
| SCHEMBL7567756 | 0.76 | HPGD (0.42) | MAPTPOLBMAPK1HPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110016021-B | Immunomodulator | 成都先导药物开发股份有限公司 | 2021-05-07 | — | — | CN | disclosed |