Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | GSK3A | P49840 | 1/20 | 0.54 |
| ▸ | GSK3B | P49841 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 5/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4498836 | 0.89 | MAPT (0.51) | ALDH1A1KDM4EHTTMAPTMEN1 | |
| SCHEMBL6677466 | 0.75 | MAPK1 (0.75) | MAPK1NPC1RAB9AGAAGSK3A | |
| SCHEMBL30173920 | 0.73 | MEN1 (0.79) | MAPK1GAAGSK3AGSK3BALDH1A1 | |
| SCHEMBL28551638 | 0.73 | MEN1 (0.79) | MAPK1GAAGSK3AGSK3BALDH1A1 | |
| SCHEMBL30173806 | 0.73 | MEN1 (0.79) | MAPK1GAAGSK3AGSK3BALDH1A1 | |
| SCHEMBL28546977 | 0.73 | MEN1 (0.79) | MAPK1GAAGSK3AGSK3BALDH1A1 | |
| SCHEMBL11244212 | 0.73 | PTGS2 (0.76) | MAPK1GAAGSK3AGSK3BALDH1A1 | |
| SCHEMBL11156647 | 0.72 | ALDH1A1 (0.78) | MAPK1NPC1RAB9AGAAGSK3A | |
| SCHEMBL28549042 | 0.71 | ALDH1A1 (0.72) | MAPK1GAAGSK3AGSK3BALDH1A1 | |
| SCHEMBL30173897 | 0.71 | ALDH1A1 (0.72) | MAPK1GAAGSK3AGSK3BALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112679470-A | (E) -1-phenyl-4-alkenyl-1H-pyrazole compound and medical application thereof | 中国药科大学 | 2021-04-20 | — | — | CN | disclosed |