⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3903537 | 0.81 | MAPT (0.36) | — | |
| SCHEMBL6465615 | 0.81 | MEN1 (0.31) | — | |
| SCHEMBL553580 | 0.80 | THRB (0.40) | — | |
| SCHEMBL8040148 | 0.74 | CA12 (0.33) | — | |
| SCHEMBL9268433 | 0.74 | MAOA (0.38) | — | |
| SCHEMBL3974124 | 0.72 | MEN1 (0.31) | — | |
| SCHEMBL2037376 | 0.71 | MAOA (0.36) | — | |
| SCHEMBL5849668 | 0.70 | TSHR (0.41) | — | |
| SCHEMBL6450964 | 0.69 | MEN1 (0.30) | — | |
| SCHEMBL8218667 | 0.69 | HSPA5 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160194424-A1 | MONOMERS FOR USE IN A POLYMERIZABLE COMPOSITION AND HIGH REFRACTIVE INDEX POLYMER FOR OPTHALMIC APPLICATIONS | CONTAMAC LIMITED (GB) | 2016-07-07 | — | — | US | claimed |
| EP-1509172-B1 | PHOTOABLATABLE CORNEA INLAYS | BAUSCH & LOMB (US) | 2013-09-04 | — | — | EP | claimed |
| EP-1828270-B1 | NANOHYBRID POLYMERS FOR OPHTHALMIC APPLICATIONS | KEY MEDICAL TECHNOLOGIES INC (US) | 2013-04-10 | — | — | EP | claimed |
| EP-2427509-A1 | POLYMER COMPOSITION | Contamac Limited (GB) | 2012-03-14 | — | — | EP | claimed |
| WO-2010128266-A1 | POLYMER COMPOSITION | CONTAMAC LIMITED (GB) | 2010-11-11 | — | — | WO | claimed |
| EP-1664855-B1 | PROCESS FOR MANUFACTURING INTRAOCULAR LENSES WITH BLUE LIGHT ABSORPTION CHARACTERISTICS | BAUSCH & LOMB (US) | 2009-03-11 | — | — | EP | claimed |
| US-20160194424-A1 | MONOMERS FOR USE IN A POLYMERIZABLE COMPOSITION AND HIGH REFRACTIVE INDEX POLYMER FOR OPTHALMIC APPLICATIONS | CONTAMAC LIMITED (GB) | 2016-07-07 | — | — | US | disclosed |
| US-8729203-B2 | Polymer composition | CONTAMAC LIMITED (GB) | 2014-05-20 | — | — | US | disclosed |
| US-20130035414-A1 | HIGH REFRACTIVE INDEX POLYMER COMPOSITION FOR OPTHALMIC APPLICATIONS | CONTAMAC LIMITED (GB) | 2013-02-07 | — | — | US | disclosed |
| EP-2427509-A1 | POLYMER COMPOSITION | Contamac Limited (GB) | 2012-03-14 | — | — | EP | disclosed |
| US-20120053313-A1 | POLYMER COMPOSITION | CONTAMAC LIMITED (GB) | 2012-03-01 | — | — | US | disclosed |
| WO-2010128266-A1 | POLYMER COMPOSITION | CONTAMAC LIMITED (GB) | 2010-11-11 | — | — | WO | disclosed |