SCHEMBL6465615

SCHEMBL6465615

[CH2]COc1cccc(O)c1-c1cccc2[nH]nnc12

nearest known ligand 0.31

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9268433 0.82 MAOA (0.38) MEN1KMT2A
SCHEMBL285497 0.81
SCHEMBL553580 0.80 THRB (0.40)
SCHEMBL3974124 0.80 MEN1 (0.31) MEN1KMT2A
SCHEMBL2037376 0.79 MAOA (0.36) MEN1KMT2A
SCHEMBL8218667 0.77 HSPA5 (0.35) MEN1KMT2A
SCHEMBL8962327 0.76 MGAM (0.39)
SCHEMBL8040148 0.76 CA12 (0.33) MEN1KMT2A
SCHEMBL29501455 0.73 MGAM (0.43)
SCHEMBL83054 0.73 MGAM (0.43)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020042484-A1 High refractive index hydrogel compositions for ophthalmic implants BAUSCH & LOMB MEXICO, S.A. DE C.V. (MX) 2002-04-11 US claimed
WO-2000079312-A1 HIGH REFRACTIVE INDEX COMPOSITIONS FOR OPHTHALMIC IMPLANTS BAUSCH & LOMB SURGICAL, INC. (US) 2000-12-28 WO claimed
US-20190119425-A1 Polymers and Methods for Ophthalmic Applications KEY MEDICAL TECH INC (US) 2019-04-25 US disclosed
EP-1546225-A1 ELASTOMERIC, EXPANDABLE HYDROGEL COMPOSITIONS BAUSCH & LOMB INCORPORATED (US) 2005-06-29 EP disclosed
EP-1465903-A1 HIGH REFRACTIVE INDEX POLYMERIC SILOXYSILANE COMPOSITIONS BAUSCH & LOMB INCORPORATED (US) 2004-10-13 EP disclosed
EP-1448571-A1 HIGH REFRACTIVE INDEX AROMATIC-BASED SILOXANE MONOFUNCTIONAL MACROMONOMERS BAUSCH & LOMB INCORPORATED (US) 2004-08-25 EP disclosed
EP-1448572-A1 HIGH REFRACTIVE INDEX POLYMERIC SILOXYSILANE COMPOSITIONS BAUSCH & LOMB INCORPORATED (US) 2004-08-25 EP disclosed
WO-2004026928-A1 ELASTOMERIC, EXPANDABLE HYDROGEL COMPOSITIONS BAUSCH & LOMB INCORPORATED (US) 2004-04-01 WO disclosed
WO-2003040157-A1 HIGH REFRACTIVE INDEX POLYMERIC SILOXYSILANE COMPOSITIONS BAUSCH & LOMB INCORPORATED (US) 2003-05-15 WO disclosed
WO-2003040158-A1 HIGH REFRACTIVE INDEX POLYMERIC SILOXYSILANE COMPOSITIONS BAUSCH & LOMB INCORPORATED (US) 2003-05-15 WO disclosed
WO-2003040155-A1 HIGH REFRACTIVE INDEX AROMATIC-BASED SILOXANE MONOFUNCTIONAL MACROMONOMERS BAUSCH & LOMB INCORPORATED (US) 2003-05-15 WO disclosed