Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | ITK | Q08881 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | TP53 | P04637 | 2/20 | 0.31 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | JAK2 | O60674 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7267358 | 0.82 | THRB (0.45) | THRBALDH1A1TP53TSHRHIF1A | |
| SCHEMBL285497 | 0.80 | — | — | |
| SCHEMBL6465615 | 0.80 | MEN1 (0.31) | — | |
| SCHEMBL6450964 | 0.79 | MEN1 (0.30) | — | |
| SCHEMBL6851614 | 0.78 | APP (0.39) | THRBALDH1A1TP53TSHRHIF1A | |
| SCHEMBL4579826 | 0.73 | THRB (0.58) | THRBALDH1A1TP53TSHRHIF1A | |
| SCHEMBL30053278 | 0.72 | THRB (0.64) | THRBALDH1A1TP53TSHRHIF1A | |
| SCHEMBL4577955 | 0.72 | THRB (0.64) | THRBALDH1A1TP53TSHRHIF1A | |
| SCHEMBL28807208 | 0.72 | TYMS (0.34) | THRB | |
| SCHEMBL8590357 | 0.71 | THRB (0.38) | THRBITKALDH1A1HSD17B10LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 239 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3207076-B1 | POLYMERS AND METHODS FOR OPTHALMIC APPLICATIONS | KEY MEDICAL TECH INC (US) | 2023-06-28 | — | — | EP | claimed |
| US-20210324125-A1 | POLYMERS AND METHODS FOR OPHTHALMIC APPLICATIONS | KEY MEDICAL TECH INC (US) | 2021-10-21 | — | — | US | claimed |
| US-20200087433-A1 | NANOHYBRID POLYMERS FOR OPHTHALMIC APPLICATIONS | KEY MEDICAL TECH INC (US) | 2020-03-19 | — | — | US | claimed |
| US-10421830-B2 | Nanohybrid polymers for ophthalmic applications | KEY MEDICAL TECHNOLOGIES, INC. (US) | 2019-09-24 | — | — | US | claimed |
| US-20190119425-A1 | Polymers and Methods for Ophthalmic Applications | KEY MEDICAL TECH INC (US) | 2019-04-25 | — | — | US | claimed |
| US-10106637-B2 | Polymers and methods for ophthalmic applications | KEY MEDICAL TECH INC (US) | 2018-10-23 | — | — | US | claimed |
| US-9820850-B2 | Polymers and methods for ophthalmic applications | KEY MEDICAL TECHNOLOGIES, INC. (US) | 2017-11-21 | — | — | US | claimed |
| EP-3207076-A1 | POLYMERS AND METHODS FOR OPTHALMIC APPLICATIONS | Key Medical Technologies, Inc. (US) | 2017-08-23 | — | — | EP | claimed |
| WO-2016061457-A1 | POLYMERS AND METHODS FOR OPTHALMIC APPLICATIONS | KEY MEDICAL TECHNOLOGIES, INC. (US) | 2016-04-21 | — | — | WO | claimed |
| US-20150274869-A1 | NANOHYBRID POLYMERS FOR OPHTHALMIC APPLICATIONS | KEY MEDICAL TECHNOLOGIES, INC. | 2015-10-01 | — | — | US | claimed |
| US-6657029-B2 | High refractive index monomer, greater amount of a hydrophilic monomer, crosslinker, and initiator; give water content; intraocular lenses | BAUSCH & LOMB INCORPORATED | 2003-12-02 | — | — | US | claimed |
| US-6657032-B2 | High refractive index and hydrophilic monomers, a crosslinker, an initiator and water | BAUSCH & LOMB INCORPORATED | 2003-12-02 | — | — | US | claimed |
| US-6657030-B2 | High refractive index and hydrophilic monomers, a crosslinker, an initiator and water | BAUSCH & LOMB INCORPORATED | 2003-12-02 | — | — | US | claimed |
| US-20020049290-A1 | High refractive index hydrogel compositions for ophthalmic implants | VANDERBILT DAVID P (US) | 2002-04-25 | — | — | US | claimed |
| US-20020042483-A1 | High refractive index hydrogel compositions for ophthalmic implants | VANDERBILT DAVID P (US) | 2002-04-11 | — | — | US | claimed |
| US-20020042484-A1 | High refractive index hydrogel compositions for ophthalmic implants | BAUSCH & LOMB MEXICO, S.A. DE C.V. (MX) | 2002-04-11 | — | — | US | claimed |
| US-20020037984-A1 | High refractive index hydrogel compositions for ophthalmic implants | VANDERBILT DAVID P (US) | 2002-03-28 | — | — | US | claimed |
| US-6329485-B1 | FOR INTRAOCULAR LENSES | BAUSCH & LOMB INCORPORATED | 2001-12-11 | — | — | US | claimed |
| WO-2000079312-A1 | HIGH REFRACTIVE INDEX COMPOSITIONS FOR OPHTHALMIC IMPLANTS | BAUSCH & LOMB SURGICAL, INC. (US) | 2000-12-28 | — | — | WO | claimed |
| WO-2000034804-A1 | HIGH REFRACTIVE INDEX HYDROGEL COMPOSITIONS FOR OPHTHALMIC IMPLANTS | BAUSCH & LOMB SURGICAL, INC. (US) | 2000-06-15 | — | — | WO | claimed |