Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 5/20 | 1.00 |
| ▸ | MAPT | P10636 | 4/20 | 1.00 |
| ▸ | USP2 | O75604 | 4/20 | 1.00 |
| ▸ | TP53 | P04637 | 4/20 | 1.00 |
| ▸ | MEN1 | O00255 | 3/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 3/20 | 1.00 |
| ▸ | MAPK1 | P28482 | 2/20 | 1.00 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 1.00 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 1.00 |
| ▸ | HPGD | P15428 | 1/20 | 0.74 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.74 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.69 |
| ▸ | PIP5K1A | Q99755 | 4/20 | 0.50 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.50 |
| ▸ | CSNK2A2 | P19784 | 2/20 | 0.48 |
| ▸ | CSNK2B | P67870 | 2/20 | 0.48 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.48 |
| ▸ | CSNK2A3 | Q8NEV1 | 2/20 | 0.48 |
| ▸ | CETP | P11597 | 3/20 | 0.45 |
| ▸ | KARS1 | Q15046 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Totarol SCHEMBL1839596 | 1.00 | CYP3A4 (1.00) | CYP3A4MAPTUSP2TP53MEN1 | |
| Totarol SCHEMBL13423504 | 1.00 | CYP3A4 (1.00) | CYP3A4MAPTUSP2TP53MEN1 | |
| Totarol SCHEMBL30105648 | 1.00 | CYP3A4 (1.00) | CYP3A4MAPTUSP2TP53MEN1 | |
| Totarol SCHEMBL16238019 | 1.00 | CYP3A4 (1.00) | CYP3A4MAPTUSP2TP53MEN1 | |
| Totarol SCHEMBL31121504 | 1.00 | CYP3A4 (1.00) | CYP3A4MAPTUSP2TP53MEN1 | |
| 19-Hydroxytotarol SCHEMBL12998342 | 0.85 | CYP3A4 (1.00) | CYP3A4MAPTUSP2TP53MEN1 | |
| 19-Hydroxytotarol SCHEMBL13423507 | 0.85 | CYP3A4 (1.00) | CYP3A4MAPTUSP2TP53MEN1 | |
| Totarol SCHEMBL31287563 | 0.85 | CYP3A4 (0.74) | CYP3A4MAPTUSP2TP53MEN1 | |
| SCHEMBL5522477 | 0.84 | CYP3A4 (0.78) | CYP3A4MAPTUSP2TP53MEN1 | |
| SCHEMBL20970940 | 0.84 | USP2 (0.82) | CYP3A4MAPTUSP2TP53MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 799 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260131121-A1 | MICRONEEDLE PATCH | DARWIN PRECISIONS CORP (TW) | 2026-05-14 | — | — | US | claimed |
| EP-3436157-B1 | METHOD AND COMPOSITION FOR TREATING SKIN CONDITIONS | OREAL (FR) | 2025-07-30 | — | — | EP | claimed |
| CN-118851849-A | Organic chemical conversion method for exchange of hydrogen and deuterium containing electron-rich aromatic ring compound | 河南工业大学 | 2024-10-29 | — | — | CN | claimed |
| CN-118680945-A | Biofilm formation regulating composition containing persimmons and dipotassium glycyrrhizinate and application thereof | 株式会社LG生活健康 | 2024-09-24 | — | — | CN | claimed |
| CN-115813822-B | High-efficiency acne-removing composition and preparation method thereof | 厦门海尼新创生物科技有限公司 | 2024-06-25 | — | — | CN | claimed |
| US-20240130979-A1 | COMPOSITIONS AND METHODS FOR TREATMENT OF SKIN CONDITIONS | Epitop, Inc. | 2024-04-25 | — | — | US | claimed |
| CN-116077423-B | Female private care gel and preparation method and application thereof | 阿基米德(广州)化妆品研究有限公司 | 2024-04-23 | — | — | CN | claimed |
| CN-117653561-A | Anti-aging active composition, application thereof and anti-aging essential oil | 长沙黛西生物科技有限公司 | 2024-03-08 | — | — | CN | claimed |
| EP-4326892-A1 | METHOD FOR SELECTING ECOBIOLOGICAL TOPICAL COMPOSITIONS AND INGREDIENTS CAPABLE OF RESTORING OR REINFORCING THE SKIN MICROBIOTA | NAOS Institute of Life Science (FR) | 2024-02-28 | — | — | EP | claimed |
| CN-117257709-A | Gum protecting and whitening tooth paste composition and preparation method thereof | 广州丽润科技有限公司 | 2023-12-22 | — | — | CN | claimed |
| EP-1898952-A2 | SYNERGISTIC MIXTURES OF AROMATIC ALCOHOLS AND DERIVATIVES THEREOF AND TROPOLONE (DERIVATIVES) | Symrise GmbH & Co. KG (DE) | 2008-03-19 | — | — | EP | claimed |
| US-20070258996-A1 | Antimicrobial compositions | THE STERILEX CORPORATION | 2007-11-08 | — | — | US | claimed |
| US-20070054967-A1 | SYNERGISTIC MIXTURES OF AROMATIC ALCOHOLS AND DERIVATIVES THEREOF AND TROPOLONE (DERIVATIVES) | SYMRISE GMBH & CO. KG (DE) | 2007-03-08 | — | — | US | claimed |
| WO-2006134160-A2 | SYNERGISTIC MIXTURES OF AROMATIC ALCOHOLS AND DERIVATIVES THEREOF AND TROPOLONE (DERIVATIVES) | SYMRISE GMBH & CO. KG (DE) | 2006-12-21 | — | — | WO | claimed |
| WO-2005073154-A1 | A METHOD OF EXTRACTING TOTAROL AND/OR A PRODUCT CONTAINING TOTAROL | MENDE DOUGLAS ANTHONY (NZ) | 2005-08-11 | — | — | WO | claimed |
| US-6881756-B2 | Method for treating skin disorders | JOHNSON & JOHNSON CONSUMER COMPANIES, INC. (US) | 2005-04-19 | — | — | US | claimed |
| JP-2005507882-A | — | — | 2005-03-24 | — | — | JP | claimed |
| EP-1435927-A2 | METHOD FOR TREATING SKIN DISORDERS | Johnson & Johnson Consumer Companies, Inc. (US) | 2004-07-14 | — | — | EP | claimed |
| US-20030104016-A1 | Method for treating skin disorders | JOHNSON & JOHNSON CONSUMER INC. | 2003-06-05 | — | — | US | claimed |
| WO-2003024436-A2 | METHOD FOR TREATING SKIN DISORDERS | JOHNSON & JOHNSON CONSUMER COMPANIES, INC. (US) | 2003-03-27 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260131121-A1 | MICRONEEDLE PATCH | LIPA, CUTA, MMP1 | CYP3A4 4752/4885MAPT 1414/4885USP2 3257/4885 |
| US-20070054967-A1 | SYNERGISTIC MIXTURES OF AROMATIC ALCOHOLS AND DERIVATIVES THEREOF AND TROPOLONE (DERIVATIVES) | NR1H3, NR1H2, CBR3 | CYP3A4 12/4885MAPT 3989/4885USP2 3439/4885 |
| US-20030104016-A1 | Method for treating skin disorders | CUTA, MGLL, LIPA | CYP3A4 1780/4885MAPT 850/4885USP2 1410/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.