SCHEMBL28552018

SCHEMBL28552018

C=C(Cc1ccccc1)c1ccc(Cl)cc1

nearest known ligand 0.61

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 3/20 0.61
MAPT P10636 1/20 0.61
MAOA P21397 2/20 0.48
MAOB P27338 2/20 0.48
GRIN2B Q13224 1/20 0.47
TDP1 Q9NUW8 1/20 0.46
CES2 O00748 1/20 0.45
CES1 P23141 1/20 0.45
NPC1 O15118 3/20 0.44
RAB9A P51151 3/20 0.44
CNR2 P34972 1/20 0.44
MEN1 O00255 1/20 0.42
KMT2A Q03164 1/20 0.42
KDM4E B2RXH2 1/20 0.42
SIGMAR1 Q99720 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2448732 0.92 L3MBTL1 (0.52) L3MBTL1MAPTMAOAMAOBTDP1
SCHEMBL163962 0.85 MAOA (0.50) L3MBTL1MAPTMAOAMAOBCES2
SCHEMBL14042627 0.82 FNTA (0.53) L3MBTL1MAPTTDP1CES2CES1
SCHEMBL28910971 0.82 SRD5A2 (0.52) L3MBTL1MAPTGRIN2BCES2CES1
SCHEMBL12722992 0.80 ALDH1A1 (0.50) L3MBTL1MAOAMAOBNPC1RAB9A
SCHEMBL28551034 0.80 L3MBTL1 (0.47) L3MBTL1MAPTCES2CES1CNR2
SCHEMBL10609924 0.80 MAOB (0.48) L3MBTL1MAPTMAOAMAOBTDP1
SCHEMBL28555686 0.80 KMT2A (0.50) L3MBTL1MAPTTDP1CES2CES1
SCHEMBL6547555 0.79 CNR2 (0.51) L3MBTL1MAPTNPC1RAB9ACNR2
SCHEMBL7767316 0.79 L3MBTL1 (0.66) L3MBTL1MAPTGRIN2BTDP1CES2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122059785-A Method for preparing 1, 1-disubstituted alkene by rhodium-catalyzed decarboxylation cracking 华南理工大学 2026-05-19 CN disclosed
CN-111978216-B Preparation method of beta-carbonyl sulfone compound 西南医科大学 2023-02-03 CN disclosed
CN-111978216-A Preparation method of beta-carbonyl sulfone compound 西南医科大学 2020-11-24 CN disclosed