Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALPI | P09923 | 2/20 | 0.40 |
| ▸ | ALPL | P05186 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 5/20 | 0.40 |
| ▸ | CA12 | O43570 | 3/20 | 0.40 |
| ▸ | MMP2 | P08253 | 2/20 | 0.35 |
| ▸ | MMP9 | P14780 | 2/20 | 0.35 |
| ▸ | MMP14 | P50281 | 2/20 | 0.35 |
| ▸ | MMP7 | P09237 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | YAP1 | P46937 | 1/20 | 0.33 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.33 |
| ▸ | TEAD2 | Q15562 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.32 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.32 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28616310 | 0.79 | ALPL (0.37) | ALPIALPLCA2CA12MMP2 | |
| SCHEMBL28815392 | 0.78 | ALPI (0.43) | ALPIALPLCA2CA12MMP2 | |
| SCHEMBL28745298 | 0.72 | ALPI (0.40) | ALPIALPLCA2CA12MMP2 | |
| SCHEMBL15206423 | 0.72 | ADORA2A (0.44) | CA2CA1S1PR2 | |
| SCHEMBL27716170 | 0.72 | MAPT (0.46) | ALPIALPLALDH1A1 | |
| SCHEMBL27593441 | 0.71 | CA2 (0.57) | ALPIALPLCA2CA12MMP2 | |
| SCHEMBL4132581 | 0.71 | YAP1 (0.41) | ALPIALPLCA2CA12MMP2 | |
| SCHEMBL576200 | 0.71 | MMP2 (0.55) | ALPIALPLCA2CA12MMP2 | |
| SCHEMBL27845902 | 0.71 | CA2 (0.36) | ALPIALPLCA2CA12MMP2 | |
| SCHEMBL26666776 | 0.70 | NQO1 (0.46) | CA12SMN1; SMN2ALDH1A1RAB9ACA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112384509-A | Furin inhibitors | 葛兰素史密斯克莱知识产权发展有限公司 | 2021-02-19 | — | — | CN | disclosed |