Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 2/20 | 0.47 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.45 |
| ▸ | CNR1 | P21554 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | CCR1 | P32246 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2853184 | 0.95 | P2RX7 (0.54) | P2RX7TRPV1CNR1KMT2AALDH1A1 | |
| SCHEMBL2854707 | 0.95 | P2RX7 (0.45) | P2RX7TRPV1CNR1KMT2AALDH1A1 | |
| SCHEMBL2854809 | 0.94 | HPGD (0.45) | P2RX7TRPV1CNR1KMT2AALDH1A1 | |
| SCHEMBL2857987 | 0.90 | CNR1 (0.43) | P2RX7TRPV1CNR1ALDH1A1KDM4E | |
| SCHEMBL2858267 | 0.87 | MAPT (0.41) | P2RX7ALDH1A1MAPTCCR1 | |
| SCHEMBL2860669 | 0.87 | TAAR1 (0.46) | P2RX7CNR1ALDH1A1KDM4EMAPT | |
| SCHEMBL2853354 | 0.86 | P2RX7 (0.63) | P2RX7TRPV1EPHX2LMNA | |
| SCHEMBL2858012 | 0.86 | CNR1 (0.46) | P2RX7TRPV1CNR1ALDH1A1KDM4E | |
| SCHEMBL2853462 | 0.86 | TRPV1 (0.42) | P2RX7TRPV1CNR1MAPTCCR1 | |
| SCHEMBL2852505 | 0.86 | ABCB1 (0.48) | TRPV1CNR1KMT2AALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | claimed |