Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | P2RX7 | Q99572 | 3/20 | 0.44 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | PLAAT3 | P53816 | 1/20 | 0.42 |
| ▸ | PLAAT5 | Q96KN8 | 1/20 | 0.42 |
| ▸ | PLAAT2 | Q9NWW9 | 1/20 | 0.42 |
| ▸ | PLAAT4 | Q9UL19 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2855322 | 0.94 | P2RX7 (0.47) | HPGDALDH1A1P2RX7TRPV1KDM4E | |
| SCHEMBL2854707 | 0.92 | P2RX7 (0.45) | HPGDALDH1A1P2RX7TRPV1KDM4E | |
| SCHEMBL2853184 | 0.92 | P2RX7 (0.54) | HPGDALDH1A1P2RX7TRPV1KDM4E | |
| SCHEMBL2856697 | 0.91 | KDM4E (0.46) | ALDH1A1P2RX7TRPV1KDM4EPLAAT3 | |
| SCHEMBL2857987 | 0.89 | CNR1 (0.43) | ALDH1A1P2RX7TRPV1KDM4EMAPT | |
| SCHEMBL2859861 | 0.87 | TAAR1 (0.51) | ALDH1A1NPSR1KDM4EKMT2APLAAT3 | |
| SCHEMBL2852221 | 0.86 | ALDH1A1 (0.46) | HPGDALDH1A1NPSR1TRPV1KDM4E | |
| SCHEMBL2854704 | 0.86 | P2RX7 (0.48) | HPGDALDH1A1P2RX7MCL1NPSR1 | |
| SCHEMBL2854705 | 0.85 | ALDH1A1 (0.46) | HPGDALDH1A1P2RX7NPSR1TRPV1 | |
| SCHEMBL2855547 | 0.85 | TAAR1 (0.54) | ALDH1A1P2RX7NPSR1KDM4EPLAAT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | claimed |