Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 1/20 | 0.40 |
| ▸ | QRFPR | Q96P65 | 3/20 | 0.39 |
| ▸ | FNTA | P49354 | 4/20 | 0.38 |
| ▸ | FNTB | P49356 | 4/20 | 0.38 |
| ▸ | CCKBR | P32239 | 1/20 | 0.38 |
| ▸ | LTA4H | P09960 | 1/20 | 0.38 |
| ▸ | CTSS | P25774 | 2/20 | 0.38 |
| ▸ | CTSL | P07711 | 1/20 | 0.38 |
| ▸ | CTSB | P07858 | 1/20 | 0.38 |
| ▸ | CTSK | P43235 | 1/20 | 0.38 |
| ▸ | TACR3 | P29371 | 1/20 | 0.38 |
| ▸ | REN | P00797 | 1/20 | 0.37 |
| ▸ | PGGT1B | P53609 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14050069 | 0.90 | OPRD1 (0.43) | FNTAFNTBPGGT1B | |
| SCHEMBL27606645 | 0.78 | ACE (0.43) | ACEQRFPRCTSSCTSLCTSB | |
| SCHEMBL25336408 | 0.76 | MAPT (0.52) | ACECTSSCTSLCTSBCTSK | |
| SCHEMBL25336411 | 0.76 | MAPT (0.52) | ACECTSSCTSLCTSBCTSK | |
| SCHEMBL5507650 | 0.76 | LTA4H (0.58) | QRFPRFNTAFNTBLTA4HPGGT1B | |
| SCHEMBL29051005 | 0.74 | ACE (0.41) | ACECTSSCTSLCTSBCTSK | |
| Trifluoroacetic Acid SCHEMBL23630169 | 0.74 | LTA4H (0.53) | QRFPRFNTAFNTBLTA4HPGGT1B | |
| Trifluoroacetic Acid SCHEMBL23630172 | 0.74 | LTA4H (0.53) | QRFPRFNTAFNTBLTA4HPGGT1B | |
| SCHEMBL24191455 | 0.74 | CTSS (0.55) | ACEQRFPRCTSSCTSLCTSB | |
| SCHEMBL28558742 | 0.73 | MME (0.38) | ACEFNTAFNTBLTA4HTACR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112714649-B | Cyclic dinucleotide derivatives and antibody drug conjugates thereof | 第一三共株式会社 | 2024-07-02 | — | — | CN | disclosed |
| CN-112714649-A | Novel cyclic dinucleotide derivatives and antibody drug conjugates thereof | 第一三共株式会社 | 2021-04-27 | — | — | CN | disclosed |