Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | KDM1A | O60341 | 2/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.38 |
| ▸ | KDM1B | Q8NB78 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2510825 | 0.83 | LTA4H (0.42) | TSHRLMNAKMT2A | |
| SCHEMBL29532976 | 0.80 | NQO2 (0.41) | ALDH1A1L3MBTL1KDM1AKCNH2KDM1B | |
| SCHEMBL1662632 | 0.80 | NQO2 (0.41) | ALDH1A1L3MBTL1KDM1AKCNH2KDM1B | |
| SCHEMBL22123429 | 0.80 | CA12 (0.36) | TDP1L3MBTL1KDM1AKCNH2KDM1B | |
| SCHEMBL28982204 | 0.80 | MEN1 (0.36) | ALDH1A1MEN1LMNAMAPTHPGD | |
| SCHEMBL29666934 | 0.80 | KDM1A (0.48) | KDM1AKCNH2KDM1B | |
| SCHEMBL855230 | 0.80 | KDM1A (0.48) | KDM1AKCNH2KDM1B | |
| SCHEMBL28694201 | 0.78 | LMNA (0.42) | MAPK1TDP1ALDH1A1L3MBTL1TSHR | |
| SCHEMBL23673676 | 0.77 | KDM1A (0.33) | TDP1L3MBTL1KDM1AKCNH2KDM1B | |
| SCHEMBL16035613 | 0.77 | KDM1A (0.33) | KDM1AKCNH2KDM1BMEN1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112724164-A | Continuous preparation method of Grignard reagent | 兰州康鹏威耳化工有限公司 | 2021-04-30 | — | — | CN | disclosed |