Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | AKR1B1 | P15121 | 4/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 6/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | ERN1 | O75460 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31644868 | 0.83 | ERN1 (0.50) | LMNAMAPTMEN1HPGDKMT2A | |
| SCHEMBL18130015 | 0.79 | EPHX2 (0.37) | LMNAMAPTSMN1; SMN2MEN1HPGD | |
| SCHEMBL28558265 | 0.78 | MAPK1 (0.42) | LMNAMAPTSMN1; SMN2MEN1HPGD | |
| SCHEMBL17997262 | 0.78 | TSHR (0.39) | LMNAMAPTSMN1; SMN2MEN1HPGD | |
| SCHEMBL17997273 | 0.75 | HPGD (0.42) | LMNAMAPTSMN1; SMN2MEN1HPGD | |
| SCHEMBL14282688 | 0.74 | PKM (0.59) | SMN1; SMN2TDP1L3MBTL1TSHRPKM | |
| SCHEMBL20090376 | 0.74 | FURIN (0.35) | KMT2AERN1 | |
| SCHEMBL5093457 | 0.74 | ESR1 (0.40) | LMNASMN1; SMN2MEN1HTTKMT2A | |
| SCHEMBL28694200 | 0.73 | ALOX15 (0.39) | LMNAMAPTSMN1; SMN2MEN1HPGD | |
| SCHEMBL1864874 | 0.73 | CES2 (0.36) | LMNAMAPTSMN1; SMN2MEN1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114105919-A | Liquid crystal compound and preparation method and application thereof | 北京八亿时空液晶科技股份有限公司 | 2022-03-01 | — | — | CN | disclosed |